Ursodeoxycholic acid - Wikipedia
网页Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria. It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus, from which its name derived. [8]
Ursodeoxycholic acid - DrugBank Online
网页Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool. 2, 3 UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years. 1, 6 UDCA was first characterized in the bile of the Chinese...
Ursodeoxycholic Acid - StatPearls - NCBI Bookshelf
网页2023年2月12日 · Ursodeoxycholic acid is a medication used in the management and treatment of cholestatic liver disease. This activity reviews the indications, mechanism of action, and contraindications for UDCA as a valuable agent in managing liver disease.
Ursodiol | C24H40O4 | CID 31401 - PubChem
网页Ursodeoxycholic acid (UDCA) is a secondary bile acid with cytoprotectant, immunomodulating, and choleretic effects. It reduces the cholesterol fraction of biliary lipids. UDCA inhibits the absorption of cholesterol in the intestine and the secretion of cholesterol into bile, decreasing biliary cholesterol saturation.
网页Acidum ursodeoxycholicum. C24H40O4. [128-13-2] Mr 392.6. DEFINITION. 3α,7 -Dihydroxy-5 -cholan-24-oic acid. β β Content: 99.0 per cent to 101.0 per cent (dried substance). CHARACTERS. Appearance: white or almost white powder. e in methylene chl. mp: about 202 °C. IDENTIFICATION. First identification: A. Second identification: B, C.
Ursodeoxycholic acid 250 mg capsules - Summary of Product
网页Active Ingredient: ursodeoxycholic acid. Company: ADVANZ Pharma See contact details. ATC code: A05AA02, A05B. About Medicine. Prescription only medicine. Healthcare Professionals (SmPC) Patient Leaflet (PIL) This information is for use by healthcare professionals. Last updated on emc: 06 Oct 2023. Quick Links. Expand All. 1.
Ursodeoxycholic acid | C24H40O4 - ChemSpider
网页ChemSpider record containing structure, synonyms, properties, vendors and database links for Ursodeoxycholic acid, 128-13-2, UDCS.
Ursodeoxycholic Acid - an overview | ScienceDirect Topics
网页Ursodeoxycholic acid is a hydrophilic secondary bile acid utilized in the treatment of primary biliary cholangitis, cholelithiasis, and other forms of cholestasis. It has been studied in NAFLD because it has a potential anti-apoptotic and anti-oxidant effect, as well as having a weak interaction with the farnesoid X receptor (FXR).
Ursodeoxycholic acid: a promising therapeutic target for
网页2019年12月1日 · Ursodeoxycholic Acid. The secondary bile acid ursodeoxycholic acid (UDCA) has long been known to have medicinal properties. As the therapeutically active component of bear bile, it has been used for centuries in traditional Chinese medicine to treat a range of conditions, while manufactured UDCA has been used for decades ….
Ursodeoxycholic acid in cholestatic liver disease: mechanisms of …
网页Ursodeoxycholic acid (UCDA) is increasingly used for the treatment of cholestatic liver diseases. Experimental evidence suggests three major mechanisms of action: (1) protection of cholangiocytes against cytotoxicity of hydrophobic bile acids, resulting from modulation of the composition of mixed ph ….