List of Aminoglycosides - Drugs.com
网页Aminoglycosides are a class of antibiotics used mainly in the treatment of aerobic gram-negative bacilli infections, although they are also effective against other bacteria including Staphylococci and Mycobacterium tuberculosis. They are often used in combination with other antibiotics.
Aminoglycoside - Wikipedia
网页Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside .
Aminoglycosides - UpToDate
网页2022年12月12日 · The aminoglycoside class of antibiotics consists of many different agents. In the United States, gentamicin, tobramycin, amikacin, plazomicin, streptomycin, neomycin, and paromomycin are approved by the US Food and Drug Administration (FDA) and are available for clinical use.
Aminoglycosides - StatPearls - NCBI Bookshelf
网页2023年7月17日 · Aminoglycosides have a broad spectrum of activity covering aerobic organisms, including gram-negative bacteria and mycobacteria. There are several drugs within the aminoglycoside class, including gentamicin, tobramycin, amikacin, neomycin, plazomicin, and streptomycin, and FDA-approved indications vary …
Aminoglycosides: An Overview - PMC - National Center for …
网页Aminoglycosides are potent, broad-spectrum antibiotics that act through inhibition of protein synthesis. The class has been a cornerstone of antibacterial chemotherapy since streptomycin (Fig. 1) was first isolated from Streptomyces griseus and …
Aminoglycosides - Aminoglycosides - MSD Manual Professional …
网页Aminoglycosides are used for. Serious gram-negative bacillary infections. Aminoglycosides are active against most gram-negative aerobic and facultative anaerobic bacilli but lack activity against anaerobes and most gram-positive bacteria, except for most staphylococci; however, some gram-negative bacilli and staphylococci are resistant.
Aminoglycosides - Aminoglycosides - MSD Manual Consumer Version
网页Aminoglycosides are a class of antibiotics used to treat serious bacterial infections, such as those caused by gram-negative bacteria (especially Pseudomonas aeruginosa). Aminoglycosides include the following:
Aminoglycosides: An Overview - PubMed
网页2016年6月1日 · Aminoglycosides are natural or semisynthetic antibiotics derived from actinomycetes. They were among the first antibiotics to be introduced for routine clinical use and several examples have been approved for use in humans. They found widespread use as first-line agents in the early days of antimicrobial chemotherapy, but were eventually ...
Aminoglycosides - SpringerLink
网页2011年11月19日 · Aminoglycosides are highly functionalized molecules that necessitate extensive protecting group strategies to isolate particular amino or hydroxyl groups for specific transformations. Some of these reactions are quite selective due to different levels of reactivity of functional groups driven by nucleophilicity and steric accessibility.
Aminoglycosides: Mechanisms of Action and Resistance
网页2017年6月21日 · Aminoglycosides are bactericidal antibiotics originally isolated from Actinomycetes species including Streptomyces and Micromonospora [9, 10]. The general mechanism of action of aminoglycosides is inhibition of protein synthesis by promotion of mistranslation and elimination of proofreading [11].
跳至内容