Aminoglycosides: An Overview - PMC - National Center for …
网页SPECTRUM OF ACTIVITY. Aminoglycosides are active against various Gram-positive and Gram-negative organisms. Aminoglycosides are particularly potent against members of the Enterobacteriaceae family, including Escherichia coli, Klebsiella pneumoniae and K. oxytoca, Enterobacter cloacae and E.
Aminoglycosides - UpToDate
网页2022年12月12日 · This topic will review basic issues related to the clinical use of parenteral aminoglycosides, including mechanism of action, spectrum of activity, and adverse effects. Dosing and monitoring of aminoglycosides and administration in certain patient populations are discussed elsewhere.
Aminoglycosides - StatPearls - NCBI Bookshelf
网页2023年7月17日 · Aminoglycosides have a broad spectrum of activity covering aerobic organisms, including gram-negative bacteria and mycobacteria. There are several drugs within the aminoglycoside class, including gentamicin, tobramycin, amikacin, neomycin, plazomicin, and streptomycin, and FDA-approved indications vary …
Aminoglycosides: Activity and Resistance | Antimicrobial Agents …
网页1999年4月1日 · The basic chemical structure required for both potency and the spectrum of antimicrobial activity of aminoglycosides is that of one or several aminated sugars joined in glycosidic linkages to a dibasic cyclitol.
Aminoglycosides: Activity and Resistance - PMC - National …
网页The basic chemical structure required for both potency and the spectrum of antimicrobial activity of aminoglycosides is that of one or several aminated sugars joined in glycosidic linkages to a dibasic cyclitol.
Aminoglycosides - SpringerLink
网页2011年11月19日 · Aminoglycosides continue to be critical therapeutics for the treatment of life-threatening infections, with many desirable characteristics including spectrum of activity, rapid bactericidal activity, predictable PK, excellent solubility and stability, and a lack of metabolism in humans and animals.
网页The aminoglycosides are a critical component of the current antibacterial arsenal. Their broad spectrum of activity, rapid bactericidal action, and favorable chemical and pharmacokinetic properties make them a clinically useful class of drugs across numerous infection types, in-cluding certain protozoal infections.
Aminoglycosides: Mechanisms of Action and Resistance
网页2017年6月21日 · The spectrum of activity, rapid bactericidal activity, and favorable chemical and pharmacokinetic properties of aminoglycosides make them a clinically useful class of drugs.
Aminoglycosides - PubMed
网页2023年7月17日 · Aminoglycosides have a broad spectrum of activity covering aerobic organisms, including gram-negative bacteria and mycobacteria. There are several drugs within the aminoglycoside class, including gentamicin, tobramycin, amikacin, neomycin, plazomicin, and streptomycin, and FDA-approved indications vary …
网页The spectrum of activity, rapid bactericidal activity, and favorable chemical and pharmacokinetic prop-erties of aminoglycosides make them a clinically useful class of drugs. Although the introduction of efficacious and less toxic agents such as the broad-spectrum β-lactam antimicro-bials led to a shift away from the use of aminoglycosides, the
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