Heat-inactivated Bifidobacterium bifidum MIMBb75 (SYN-HI …
网页2020年4月8日 · The findings show that non-viable, heat-inactivated (HI) B bifidum MIMBb75 (SYN-HI-001) improves IBS and its symptoms significantly more than does placebo, and thus are the first demonstration of substantial and clinically relevant efficacy of non-viable bacteria in the treatment of IBS. The treatment was not associated with any safety risk and ...
Heat-inactivated Bifidobacterium bifidum MIMBb75 (SYN-HI …
网页We aimed to assess the efficacy of non-viable, heat-inactivated (HI) B bifidum MIMBb75 (SYN-HI-001) in the treatment of IBS and its symptoms.
Randomised clinical trial: Bifidobacterium bifidum MIMBb75 ...
网页Bifidobacterium bifidum MIMBb75 effectively alleviates global IBS and improves IBS symptoms simultaneously with an improvement of quality of life. Considering the high efficacy of MIMBb75 in IBS along with the good side-effect profile, MIMBb75 is a promising candidate for IBS therapy.
Effect of Bifidobacterium bifidum on Clinical Characteristics and …
网页2022年2月7日 · Furthermore, heat-inactivated B. bifidum MIMBb75 (SYN-HI-001) has been shown to substantially alleviate the symptoms of irritable bowel syndrome . B. bifidum G9-1 (BBG9-1) improves dysbiosis, which results in an increase in organic acids and improved neurotransmission (including dopamine) .
Randomised clinical trial: Bifidobacterium bifidum MIMBb75 ...
网页In this study, B. bifidum MIMBb75 significantly improved global IBS as well as its related symptoms such as pain/discomfort, distension/bloating and digestive disorders compared with placebo. Moreover, B. bifidum MIMBb75 also significantly improved the quality of life. These benefits persisted within the consumption-free wash-out phase.
Heat-inactivated Bifidobacterium bifidum MIMBb75 (SYN-HI …
网页2020年4月8日 · This study shows that B bifidum HI-MIMBb75 substantially alleviates IBS and its symptoms in a real-life setting. These results indicate that specific beneficial bacterial effects are mediated independently of cell viability.
Nonviable, Heat-inactivated Bifidobacterium bifidum MIMBb75 …
网页2020年4月24日 · Use of a heat-inactivated form of the probiotic Bifidobacterium bifidum (B bifidum) MIMBb75 (SYN-HI-001) was associated with significant reduction in abdominal pain as well as relief of symptoms in patients with irritable bowel syndrome (IBS) for at least 50% of the treatment period.
Impact of Bifidobacterium bifidum MIMBb75 on mouse …
网页Bifidobacterium bifidum MIMBb75 is a recently identified probiotic. However, its distribution along the intestine and impact on resident microbiota is unknown. Herein, we established a quantitative real-time polymerase chain reaction assay targeting the B. bifidum-specific BopA region for the quanti ….
Supplementation With Bifidobacterium and Symptomatic Control …
网页2023年8月31日 · Heat-inactivated Bifidobacterium bifidum MIMBb75 (SYN-HI-001) in the treatment of irritable bowel syndrome: a multicentre, randomised, double-blind, placebo-controlled clinical trial. Andresen V, Gschossmann J, Layer P. Lancet Gastroenterol Hepatol.
Inactivated probiotic effective against irritable bowel syndrome
网页2020年4月30日 · With funding from Synformulas GmbH, which has patented B. bifidum MIMBb75, the researchers randomly assigned 443 adult patients meeting Rome III criteria for IBS to active treatment or placebo.
跳至内容