Pathogenesis and virulence of Candida albicans - PMC
网页2021年12月29日 · The phylum Ascomycota contains some of the most successful human pathogens; these include virulent fungi that can infect individuals without immune compromise such as Histoplasma, Blastomyces, Coccidioides, and Paracoccidioides species as well as opportunistic fungi that cause disease primarily in immunosuppressed individuals such as Aspergillus...
Pathogenesis and virulence of Candida albicans - Taylor
网页2021年12月29日 · Upon fungal sensing, vaginal epithelial cells activate early mitochondrial signaling characterized by a protective type I interferon response that is shared between C. albicans and non-albicans Candida species (i.e. C. …
Candida albicans pathogenicity mechanisms - PubMed
网页2013年2月15日 · The polymorphic fungus Candida albicans is a member of the normal human microbiome. In most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain circumstances, however, C. albicans can cause infections that range from superficial infections of the skin to life-threatenin ….
Candida albicans—The Virulence Factors and Clinical …
网页2021年1月22日 · At least 15 different Candida spp. can cause infections in humans. However, five pathogens cause the most invasive infections: Candida albicans, Candida glabrata, Candida tropicalis, Candida parapsilosis, and Candida krusei, but the most common pathogen in the clinical setting is C. albicans [141].
Mechanism of Candida pathogenesis: revisiting the vital drivers
网页2020年5月6日 · Several factors play important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits, morphological and phenotypic switching, biofilm formation, tissue damaging extracellular hydrolytic enzymes, metabolic flexibility, genome plasticity, adaptation to environmental pH fluctuation, robust nutrient acquisition system ...
Candida albicans pathogenicity mechanisms - PMC - National …
网页2013年2月2日 · The polymorphic fungus Candida albicans is a member of the normal human microbiome. In most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain circumstances, however, C. albicans can cause infections that range from superficial infections of the skin to life-threatening systemic infections.
Pathogenesis and virulence of Candida albicans - PubMed
网页Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic immunosuppression, and/or medical interventions that impair the integrity of the mucocutaneous barrier and/or perturb protective h</span> …
Candida albicans - Biology, molecular characterization, pathogenicity ...
网页2018年4月1日 · Candida albicans is an emerging multidrug-resistant fungal pathogen representing an important source of invasive disease in humans and generating high healthcare costs worldwide. This fungus is frequently found in different anatomical sites of healthy persons and could induce systemic and superficial infections under optimal environmental ...
Candida albicans Pathogenesis: Fitting within the Host-Microbe …
网页The DRF outlines six classifications of host damage outcomes based on the microbe and the strength of the immune response. In this review, we revisit this concept from the perspective of Candida albicans, a microbial pathogen uniquely adapted to its human host. This fungus commonly colonizes various anatomical sites without causing notable damage.
Candida albicans pathogenicity mechanisms - Taylor & Francis …
网页2013年1月9日 · Abstract. The polymorphic fungus Candida albicans is a member of the normal human microbiome. In most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain circumstances, however, C. albicans can cause infections that range from superficial infections of the skin to life-threatening systemic infections.
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