Carboxamide - an overview | ScienceDirect Topics
网页2012年10月8日 · Carboxamide - an overview | ScienceDirect Topics. In subject area: Chemistry. Nagelamide L (21) is an isomer of nagelamide B (8) wherein the acylpyrrole unit is connected through C9-oxygen forming an ester rather than the usual carboxamide found in this family of natural products. From: Studies …
Amide - Wikipedia
网页In organic chemistry, an amide, [1][2][3] also known as an organic amide or a carboxamide, is a compound with the general formula R−C (=O)−NR′R″, where R, R', and R″ represent any group, typically organyl groups or hydrogen atoms. [4][5] The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bo...
Carboxamide | chemical compound | Britannica
网页Other articles where carboxamide is discussed: amide: The carboxamides (R′CONR2), which are derived from carboxylic acids (R′COOH), are the most important group. Sulfonamides (RSO2NR2) are similarly related to the sulfonic acids (RSO3H).
carboxamide (CHEBI:37622) - EMBL-EBI
网页carboxamide: ChEBI ID CHEBI:37622: Definition An amide of a carboxylic acid, having the structure RC(=O)NR 2. The term is used as a suffix in systematic name formation to denote the ‒C(=O)NH 2 group including its carbon atom. Stars
Carboxamide - an overview | ScienceDirect Topics
网页2012年10月8日 · A carboxamide is a type of chemical derivative similar to carbamazepine and oxcarbazepine, commonly used in the treatment of seizure disorders like Lennox-Gastaut syndrome. AI generated definition based on: Drugs During Pregnancy and Lactation (Third Edition), 2015
Comprehensive Overview of Carboxamide Derivatives as …
网页2022年1月18日 · Carboxamide derivatives represented an important class of SDHIs with broad spectrum of antifungal activities. In this review, the development of carboxamide derivatives as SDHIs with great significances were summarized.
Unexpected reactivity and mechanism of carboxamide activation …
网页2013年10月23日 · We find no suitably positioned residues near the active site of PglB that can activate the acceptor asparagine by deprotonation, making a general base mechanism unlikely and leaving carboxamide...
Catalytic and non-catalytic amidation of carboxylic acid substrates
网页2021年6月13日 · Carboxamides can be regarded as a substantial part of organic and medicinal chemistry due to their utility in synthesizing peptides, lactams, and more than 25% of familiar drugs. Moreover, they play a leading role in the synthesis of bioactive products with anticancer, antifungal, and antibacterial properties.
Pyrrole carboxamide introduction in the total synthesis of pyrrole ...
网页2021年3月8日 · In this review various strategies for the incorporation of the signature pyrrole carboxamide moiety in the total syntheses of pyrrole–imidazole alkaloids (PIA) are discussed. These so-called oroidin alkaloids have a broad range of biological activities and display interesting skeletal diversity and complexit Synthetic methodology in OBC
Synthetic strategies of indole 2 and 3-carboxamides
网页2020年5月12日 · Considering the studies of investigating the inhibitory activity of indole derivatives, the presence of carboxamide moiety at positions 2 and 3 is significant from two aspects. 1) NH and CO-carboxamide form hydrogen bonds with enzymes or proteins. 2) Polar groups can bond to the carboxamide moiety and …
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