Chronic recurrent multifocal osteomyelitis (CRMO)
网页What is chronic recurrent multifocal osteomyelitis (CRMO)? CRMO—also called chronic nonbacterial osteomyelitis (CNO)—is a rare disorder that causes inflammation of the bone. CRMO is an autoimmune disease, in which the immune system mistakenly attacks healthy tissue and organs, causing inflammation.
Chronic Recurrent Multifocal Osteomyelitis (CRMO): …
网页2017年10月27日 · Chronic non-bacterial osteomyelitis (CNO) with its most severe form chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory bone disorder. We summarize the clinical presentation, diagnostic approaches, most recent advances in understanding the pathophysiology, and available treatment options and outcomes in CNO/CRMO.
Consensus Treatment Plans for Chronic Nonbacterial Osteomyelitis ...
网页Results. Three consensus treatment plans (CTPs) were developed for the first 12 months of therapy for CNO patients refractory to NSAID monotherapy and/or with active spinal lesions. The three CTPs are: (1) methotrexate or sulfasalazine, (2) tumor necrosis factor (TNF)-alpha inhibitors with optional use of methotrexate, and (3) bisphosphonates.
Chronic Recurrent Multifocal Osteomyelitis (CRMO): …
网页CNO/CRMO is an autoinflammatory bone disorder resulting from imbalanced cytokine expression from innate immune cells. Though the exact molecular pathophysiology remains unclear, variable molecular defects appear to result in inflammasome activation and pro-inflammatory cytokine expression in monocytes from CNO/CRMO patients.
American College of Rheumatology
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Chronic nonbacterial osteomyelitis (CNO)/chronic recurrent ... - UpToDate
网页2024年6月17日 · Chronic nonbacterial osteomyelitis (CNO)/chronic recurrent multifocal osteomyelitis (CRMO) is a chronic, sterile, inflammatory disorder in children that primarily affects the bones and can cause bone destruction if untreated [1-4].
Chronic Recurrent Multifocal Osteomyelitis (CRMO) Program
网页CRMO is a severe form of chronic nonbacterial osteomyelitis (CNO). It may affect 1 or more bones. Symptoms may come and go for years. CRMO happens because the immune system attacks the bones and causes inflammation, although there is no infection. In most cases, the cause of the autoimmune response is not known.
Management of chronic recurrent multifocal osteomyelitis: …
网页2022年5月23日 · Chronic recurrent multifocal osteomyelitis (CRMO) is a rare auto-inflammatory disorder that can lead to severe bone damage at a young age. The CARRA consensus is the first developed plan to standardize CRMO management. Non-steroidal anti-inflammatory drugs are usually used as a first-line treatment.
Chronic Recurrent Multifocal Osteomyelitis (CRMO)
网页Chronic Recurrent Multifocal Osteomyelitis (CRMO), also known as Chronic Non-infectious Osteomyelitis (CNO), is a rare condition that involves inflammation of one or more bones that can be chronic (long-term). It is a fluctuating condition, which means that symptoms can come and go over time.
What Is Chronic Recurrent Multifocal Osteomyelitis (CRMO)? - WebMD
网页2022年7月23日 · Written by Alyssa Anderson. What Causes CRMO? Who Gets CRMO? What Are CRMO Symptoms? How Is CRMO Diagnosed? 5 min read. Chronic recurrent multifocal osteomyelitis (CRMO) is an...