Chronic nonbacterial osteomyelitis (CNO)/chronic recurrent ... - UpToDate
网页2024年6月17日 — Chronic nonbacterial osteomyelitis (CNO)/chronic recurrent multifocal osteomyelitis (CRMO) is a chronic, sterile, inflammatory disorder in children that primarily affects the bones and can cause bone destruction if untreated [1-4]. CNO can be sporadic or occur as part of a monogenic autoinflammatory condition such as deficiency of interleukin 1 ...
Chronic Recurrent Multifocal Osteomyelitis (CRMO): …
网页2017年10月27日 — Chronic non-bacterial osteomyelitis (CNO) with its most severe form chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory bone disorder. We summarize the clinical presentation, diagnostic approaches, most recent advances in understanding the pathophysiology, and available treatment options and outcomes in CNO/CRMO.
慢性非细菌性骨髓炎/慢性复发性多灶性骨髓炎 - UpToDate
网页慢性非细菌性骨髓炎 (chronic nonbacterial osteomyelitis, CNO)/慢性复发性多灶性骨髓炎 (chronic recurrent multifocal osteomyelitis, CRMO)是发生于儿童的无菌性慢性炎性疾病，主要累及骨骼，不治疗时可破坏骨骼 [ 1-4 ]。. CNO可为散发，也可为单基因自身炎性疾病的表现，如IL-1受体 ...
What is CRMO (Chronic Recurrent Multifocal Osteomyelitis)?
网页2024年9月12日 — Chronic recurrent multifocal osteomyelitis (CRMO) is characterized as an auto-inflammatory bone disorder, which means it results from the immune system causing inflammation without any infection present. The current medical terminology puts CRMO under the umbrella term of CNO (or chronic nonbacterial osteomyelitis), and it serves as a diagnosis ...
Chronic Recurrent Multifocal Osteomyelitis: Review - AJR
网页2012年11月23日 — CRMO is a diagnosis of exclusion based on the following criteria: lack of causative organism; no abscess formation, fistula, or sequestra; atypical location compared with infectious osteomyelitis, with frequent involvement of the clavicle and often showing multifocality; radiographic appearance of subacute or chronic osteomyelitis; nonspecific h...
Adult-onset Chronic Recurrent Multifocal Osteomyelitis with …
网页2017年9月1日 — Chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory bone disorder that generally occurs in children and predominantly affects the long bones with marginal sclerosis. We herein report two cases of adult-onset CRMO involving the tibial diaphysis bilaterally, accompanied by polyarthritis.
Chronic recurrent multifocal osteomyelitis - Radiopaedia.org
网页2024年5月30日 — Chronic recurrent multifocal osteomyelitis (CRMO) is an idiopathic inflammatory bone disorder seen primarily in children and adolescents. It is often a diagnosis of exclusion once underlying infection and neoplasia have been ruled out.
Chronic Recurrent Multifocal Osteomyelitis (CRMO): …
网页CNO/CRMO is an autoinflammatory bone disorder resulting from imbalanced cytokine expression from innate immune cells. Though the exact molecular pathophysiology remains unclear, variable molecular defects appear to result in inflammasome activation and pro-inflammatory cytokine expression in monocytes from CNO/CRMO patients.
Clinical and Diagnostic Considerations for Atypical, Adult Onset ...
网页2019年9月29日 — Nonbacterial osteitis (NBO) is a rare autoinflammatory bone disease with a presentation of acute or recurrent, unifocal or multifocal sterile bone lesions, and it is referred to as chronic recurrent multifocal osteomyelitis (CRMO) in cases where the bone lesions are recurrent and multifocal.
Management of chronic recurrent multifocal osteomyelitis: …
网页2022年5月23日 — Chronic recurrent multifocal osteomyelitis (CRMO) is a rare auto-inflammatory disorder that can lead to severe bone damage at a young age. The CARRA consensus is the first developed plan to standardize CRMO management. Non-steroidal anti-inflammatory drugs are usually used as a first-line treatment.
- 某些结果已被删除