Fludarabine - Wikipedia
网页Fludarabine is a purine analogue and antineoplastic agent. It is generally used as its 5-O-phosphorylated form known as fludarabine phosphate, sold under the brand name Fludara among others. It is a chemotherapy medication used …
网页phosphate intended for intravenous administration. The chemical name for fludarabine phosphate is 9H-Purin-6-amine, 2-fluoro-9-(5-0-phosphono. β-D-arabino-furanosyl) (2-fluoro-ara-AMP). The...
Fludarabine: Uses, Interactions, Mechanism of Action - DrugBank …
网页Fludarabine is a chemotherapy drug used in the treatment of chronic lymphocytic leukemia. It acts at DNA polymerase alpha, ribonucleotide reductase and DNA primase, results in the inhibition of DNA synthesis, and destroys the cancer cells. Mechanism of action
DailyMed - FLUDARABINE PHOSPHATE injection, powder, …
网页2022年9月30日 · Fludarabine Phosphate for Injection, USP contains fludarabine phosphate USP, a fluorinated nucleotide analog of the antiviral agent vidarabine, 9-β-D-arabinofuranosyladenine (ara-A) that is ... CLINICAL PHARMACOLOGY.
网页The chemical name for fludarabine phosphate is 9H-Purin-6-amine, 2-fluoro-9-(5-Q-phosphono 34 . ß-D-arabino-furanosyl) (2-fluoro-ara-AMP). The molecular formula of fludarabine phosphate is ....
Fludarabine | C10H12FN5O4 | CID 657237 - PubChem
网页Fludarabine | C10H12FN5O4 | CID 657237 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Fludarabine Monograph for Professionals - Drugs.com
网页2024年7月22日 · Fludarabine (Monograph) Brand name: Fludara. Drug class: Antineoplastic Agents. VA class: AN300. Chemical name: 2-Fluoro-9- (5-O-phosphono-β-D-arabinofuranosyl)9H -purin-6-amine. Molecular formula: C 10 H 13 FN 5 O 7 P. CAS number: 75607-67-9. Medically reviewed by Drugs.com on Jul 22, 2024. Written by ASHP. Introduction. Uses. Dosage. Warnings.
FLUDARABINE PHOSPHATE injection - DailyMed
网页2023年2月14日 · Fludarabine Phosphate Injection is indicated for the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen.
Fludarabine - an overview | ScienceDirect Topics
网页Fludarabine is a cell cycle-specific drug that inhibits DNA synthesis at multiple levels by interfering with the catalytic activity of various enzymes, including the ribonucleotide reductase, DNA primase, and human DNAP α and ɛ.
Pharmacotherapy Update: Fludarabine in the Treatment of Non …
网页2009年5月11日 · Fludarabine, a purine nucleoside analogue, is considered as the most active drug in chronic lymphocytic leukemia. This review summarizes current knowledge concerning the mechanism of action, pharmacological properties, clinical activity and toxicity of fludarabine in the treatment of non-Hodgkin's lymphoma.
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