GHB Effects: Physical Side Effects, Overdose and Withdrawal
网页2020年2月27日 · Gamma-hydroxybutyrate, or GHB, is a potent central nervous system depressant that has dramatic effects on the mind and body. Most people take GHB recreationally for the euphoric and calming effects it produces at low doses.
GHB Drug: Effects, Hazards & Methods of Abuse - Drugs.com
网页Euphoria, increased sex drive, and tranquility are reported positive effects of GHB abuse. However, immediate negative effects of GHB use may include: sweating; loss of consciousness; nausea; auditory and visual hallucinations; headaches; vomiting; exhaustion; sluggishness; amnesia; confusion; clumsiness; GHB can have an addictive potential if ...
γ-Hydroxybutyric acid - Wikipedia
网页γ-Hydroxybutyric acid (GHB) (or gamma-hydroxybutyric acid), also known as 4-hydroxybutanoic acid is a naturally occurring neurotransmitter and a depressant drug. It is a precursor to GABA, glutamate, and glycine in certain brain areas. It acts on the GHB receptor and is a weak agonist at the GABA B receptor.
Current Insights on the Impact of Gamma-Hydroxybutyrate (GHB) …
网页2022年2月9日 · Recreational gamma-hydroxybutyrate (GHB) use, although less common than other substance use, is increasingly recognised and is over-represented in emergency toxicology presentations. This narrative review summarizes GHB pharmacology, current patterns of use, potential harms and management of GHB toxicity and withdrawal.
Gamma-Hydroxybutyrate Toxicity - StatPearls - NCBI Bookshelf
网页2023年8月8日 · Lower doses of GHB (10 mg/kg) have amnestic and variable sedative effects. Doses of 20 mg/kg to 30 mg/kg lead to cycles of rapid eye movement (REM) sleep. Higher doses (50 mg/kg) result in bradycardia, respiratory depression, and coma.
网页GHB greatly increases the CNS depressant effects of alcohol and other depressants. What is its effect on the body? GHB takes effect in 15 to 30 minutes, and the effects last 3 to 6 hours. Low doses of GHB produce nausea. At high doses, GHB overdose can result in: • Unconsciousness, seizures, slowed heart rate, greatly
Gamma-hydroxybutyrate Abuse: Pharmacology and Poisoning and …
网页2020年4月9日 · Gamma-hydroxybutyrate (GHB) is a central nervous system depressant primarily used as a recreational drug of abuse, but also for the treatment of narcolepsy with cataplexy in adult patients and as an adjuvant for control of alcohol withdrawal syndrome. The main aim of this review is to summarise updated knowledge about GHB pharmacokinetics and ...
GHB Effects on Cognitive Function: Exploring the Drug's Impact …
网页2024年9月30日 · The effects of GHB on cognitive function are complex and multifaceted, and we’re only just beginning to scratch the surface. What we do know is that GHB has profound effects on the brain’s neurotransmitter systems, particularly GABA and dopamine. These effects can lead to short-term changes in memory, attention, and …
GHB Addiction: Signs, Side Effects & Treatment
网页2024年9月17日 · GHB (gamma hydroxybutyrate) is a central nervous system (CNS) depressant drug with effects similar to alcohol and other drugs. It’s often referred to as “liquid ecstasy” due to its potent effects. GHB slows the activity in the CNS, producing a soothing effect. This creates feelings of relaxation and euphoria.
12. G-Hydroxybutyrate (GHB) Overdose and Withdrawal
网页GHB is a structural precursor of GABA with agonist activity at both GHB receptors and GABA-B receptors (usually at higher doses), rapidly leading to CNS depression. GHB receptors can lead to changes in serotonin, dopamine, opioid and other neurotransmitters in the CNS, which can result in euphoria, but also stimulant effects.