Granulocyte-macrophage colony-stimulating factor - Wikipedia
网页Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells …
粒细胞-巨噬细胞集落刺激因子（GM-CSF）的来源、功能与疾病
网页gm-csf 粒细胞-巨噬细胞集落刺激因子（GM-CSF），也称为集落刺激因子2（CSF2），是单体糖蛋白，通过分泌巨噬细胞，T细胞，肥大细胞，自然杀伤细胞，内皮细胞和成纤维细胞，其功能如同一个细胞因子。
GM-CSF: A Promising Target in Inflammation and Autoimmunity
网页2020年10月29日 · The cytokine, granulocyte macrophage-colony stimulating factor (GM-CSF), was firstly identified as being able to induce in vitro the proliferation and differentiation of bone marrow progenitors into granulocytes and macrophages.
Granulocyte-macrophage colony-stimulating factor: an ... - Nature
网页2021年7月19日 · GM-CSF stimulates the production of neutrophils and monocytes by the bone marrow and maintains the activation and survival of monocytes. GM-CSF restored cytokine secretion in monocytes from...
逐典细胞因子GM-CSF：一种调控炎症反应的细胞因子及其在治疗 …
网页2024年2月20日 · GM-CSF作为一种关键的细胞因子，在调控免疫反应和维持组织稳态中发挥着至关重要的作用。. 其在肺部稳态和炎症中的独特作用，使得它成为研究肺部疾病和自身免疫性疾病的重要靶点。. 深入了解GM-CSF的生物学功能，以及开发针对其信号通路的治疗药 …
粒细胞-巨噬细胞集落刺激因子 - 维基百科，自由的百科全书
网页粒细胞-巨噬细胞集落刺激因子 （granulocyte-macrophage colony-stimulating factor，GM-CSF），又名 集落刺激因子2 （colony-stimulating factor 2，CSF2），是由 巨噬细胞 、 T细胞 、 肥大细胞 、 自然杀伤细胞 、 內皮 细胞和 成纤维细胞 分泌的一种 单体 醣蛋白 细胞因子。 沙格司亭 （英语：sargramostim） 和 莫拉司亭 是天然存在的GM-CSF的 藥品 类似物。
GM-CSF: An immune modulatory cytokine that can suppress ... - PubMed
网页GM-CSF was originally identified as a colony stimulating factor (CSF) because of its ability to induce granulocyte and macrophage populations from precursor cells. Multiple studies have demonstrated that GM-CSF is also an immune-modulatory cytokine, capable of affecting not only the phenotype of mye ….
GM-CSF: A Double-Edged Sword in Cancer Immunotherapy
网页2022年7月5日 · Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that drives the generation of myeloid cell subsets including neutrophils, monocytes, macrophages, and dendritic cells in …
Cytokines Focus: GM-CSF in inflammation - PMC - National …
网页2020年1月1日 · GM-CSF is a potential therapeutic target in inflammation and autoimmunity. This study reviews the literature on the biology of GM-CSF, in particular that describing the research leading to clinical trials targeting GM-CSF and its receptor in numerous inflammatory/autoimmune conditions, such as rheumatoid arthritis.
GM-CSF in inflammation - PubMed
网页2020年1月6日 · Granulocyte-macrophage colony-stimulating factor (GM-CSF) has many more functions than its original in vitro identification as an inducer of granulocyte and macrophage development from progenitor cells. Key features of GM-CSF biology need to be defined better, such as the responding and producing cell types, its links with other mediators, its ...