A current view on inflammation | Nature Immunology
网页2017年7月19日 · Kastner and colleagues review monogenic inflammatory diseases caused by mechanisms as varied as dysregulated inflammasomes, perturbations in ubiquitination, protein folding or complement...
Inflammatory responses and inflammation-associated diseases …
网页2018年1月1日 · Inflammation is the immune system's response to harmful stimuli, such as pathogens, damaged cells, toxic compounds, or irradiation [1], and acts by removing injurious stimuli and initiating the healing process [2]. Inflammation is therefore a defense mechanism that is vital to health [3].
Acute Inflammatory Response - StatPearls - NCBI Bookshelf
网页2024年6月8日 · Acute inflammation is an immediate, adaptive response with limited specificity caused by noxious stimuli, such as infection and tissue damage. This beneficial response protects against infectious organisms, including Mycobacterium tuberculosis, protozoa, fungi, and other parasites.
A guiding map for inflammation | Nature Immunology
网页2017年7月19日 · Here, we provide a general guide to the cellular and humoral contributors to inflammation as well as to the pathways that characterize inflammation in specific organs and tissues.
A 360° view of the inflammasome: Mechanisms of activation, cell …
网页2023年5月25日 · Inflammasomes are critical initiators of inflammation and adaptive immunity with far-reaching effects on human health and disease. Inflammasome activation is an innate immune response that fundamentally alters the cellular state, through the initiation of pyroptosis, cell death, and inflammatory cytokine release.
Inflammatory mechanisms: the molecular basis of inflammation …
网页A coordinated series of common effector mechanisms of inflammation contribute to tissue injury, oxidative stress, remodeling of the extracellular matrix, angiogenesis, and fibrosis in diverse target tissues. Atherosclerosis provides an example of a chronic disease that involves inflammatory mechanisms.
Origin and physiological roles of inflammation | Nature
网页2008年7月1日 · Inflammation is an adaptive response that is triggered by noxious stimuli and conditions, such as infection and tissue injury 1, 2. Considerable progress has been made in...
What Exactly Is Inflammation (and What Is It Not?)
网页2022年11月28日 · Inflammation is a physiological, tightly regulated, protective response to an underlying infectious or non-infectious process or condition that involves cells of the innate immune system, adaptive immune system, and inflammatory mediators; it is not a pathological response, despite the over 3000 disease conditions that end in “-itis”, a ...
Inflammation: Pathogenesis and Biological Markers
网页This introductory chapter reviews general mechanisms of inflammation which apply to specific inflammatory conditions, including diabetes and obesity. We review the history of inflammation, its pathogenetic mechanisms, the role of innate and adaptive immune systems, clinically useful biomarkers, and current anti-inflammatory therapeutic strategies.
An overview of inflammation: mechanism and consequences
网页2011年7月29日 · Inflammation is an essential response provided by the immune systems that ensures the survival during infection and tissue injury. Inflammatory responses are essential for the maintenance of normal tissue homeostasis. The molecular mechanism of inflammation is quite a complicated process which is …