MONOGENIC中文(简体)翻译：剑桥词典 - Cambridge Dictionary
网页adjective. biology specialized / ˌmɒn.əˈdʒen.ɪk / / ˌmɑː.nəˈdʒen.ɪk / Add to word list. relating to or controlled by a single gene (= part of a cell that is passed on by your parents and …
Monogenic Definition & Meaning - Merriam-Webster
网页2024年4月16日 · The meaning of MONOGENIC is of, relating to, or controlled by a single gene and especially by either of an allelic pair.
Human Genetic Disorders: Studying Single-Gene (Mendelian
网页2015年3月19日 · Most diseases are caused by mutations in more than one gene. So what clues can monogenic, or single-gene disorders provide?
Monogenic disease - Definition and Examples - Biology Online
网页2023年8月25日 · A monogenic disease is a diseased condition determined by the interaction of a single gene. This is in contrast to a polygenic condition wherein several genes (polygene) are involved. Monogenic diseases result from single-gene mutations that disrupt the normal functioning of the gene’s protein product.
MONOGENIC | definition in the Cambridge English Dictionary
网页relating to or controlled by a single gene (= part of a cell that is passed on by your parents and that controls physical development, behavior, etc.): The research team is trying to …
Gene therapy for monogenic disorders: challenges, strategies, and ...
网页Monogenic disorders refer to a group of human diseases caused by mutations in single genes. While disease-modifying therapies have offered some relief from symptoms and delayed progression for some monogenic diseases, most of these diseases still lack effective treatments.
Application of full-genome analysis to diagnose rare monogenic …
网页2021年9月23日 · The Full-Genome Analysis method, FGA, combines long-range assembly and whole-genome sequencing to detect small variants, structural variants with breakpoint resolution, and phasing. We built a ...
Inheritance patterns of monogenic disorders (Mendelian and non ...
网页2023年7月6日 · This topic review discusses the inheritance patterns of monogenic traits, including classic Mendelian inheritance patterns as well as non-Mendelian inheritance patterns such as mitochondrial inheritance and sex-linked expression, along with other factors that can modify trait expression.
Maximizing insights from monogenic immune disorders - PMC
网页Monogenic immune disorders provide unprecedented insights into the consequences of disrupting single genes in humans, thereby informing our understanding of fundamental immune function and disease. Genomics has accelerated monogenic disease discovery while also revealing the complexity of human disease, …
Monogenic diabetes - Nature Reviews Disease Primers
网页2023年3月9日 · Monogenic diabetes is a heterogeneous group of disorders that includes various clinical conditions associated with hyperglycaemia, which are mostly due to impaired function or altered development...