Thermogenin - Wikipedia
网页Thermogenin (called uncoupling protein by its discoverers and now known as uncoupling protein 1, or UCP1) [5] is a mitochondrial carrier protein found in brown adipose tissue (BAT). It is used to generate heat by non-shivering thermogenesis , and makes a quantitatively important contribution to countering heat loss in babies which would ...
產熱素 - 维基百科，自由的百科全书
网页產熱素 （Thermogenin），被發現者稱為 解偶聯蛋白，現在稱為解偶聯蛋白1（UCP1） [5] 是在 棕色脂肪 組織（BAT） 線粒體 中發現的解偶聯蛋白。. 它用於通過不發抖的 生熱 （英语：Thermogenesis） 來產生熱量，並且在定量上對抵抗嬰兒的熱量損失做出了重要的貢獻 ...
产热素 - 维基百科，自由的百科全书
网页产热素（Thermogenin），被发现者称为解偶联蛋白，现在称为解偶联蛋白1（UCP1） [5] 是在棕色脂肪组织（BAT）线粒体中发现的解偶联蛋白。 它用于通过不发抖的 生热 （ 英语 ： Thermogenesis ） 来产生热量，并且在定量上对抵抗婴儿的热量损失做出了重要的贡献 ...
Thermogenin - an overview | ScienceDirect Topics
网页Thermogenin or uncoupling protein (UCP) is a 33kDa dimeric protein found in the inner mitochondrial membrane of brown adipose tissue which supplies heat by allowing the dissipation of the proton gradient without ATP synthesis. …
The uncoupling protein, thermogenin - PubMed
网页The uncoupling protein (UCP) or thermogenin is a 33 kDa inner-membrane mitochondrial protein exclusive to brown adipocytes in mammals that functions as a proton transporter, allowing the dissipation as heat of the proton gradient generated by the respiratory chain and thereby uncoupling oxidative phosphorylation.
Thermogenic Fat: Development, Physiological Function, and …
网页2021年5月31日 · The concerning worldwide increase of obesity and chronic metabolic diseases, such as T2D, dyslipidemia, and cardiovascular disease, motivates further investigations into preventive and alternative therapeutic approaches.
The cellular and functional complexity of thermogenic fat
网页2021年3月23日 · Brown and beige adipocytes are mitochondria-enriched cells capable of dissipating energy in the form of heat. These thermogenic fat cells were originally considered to function solely in heat ...
Targeting thermogenesis in brown fat and muscle to treat
网页2017年10月23日 · Key Points. Cold-induced thermogenesis is an important component of total energy expenditure and contributes to overall energy balance. Brown adipose tissue (BAT) has been known to be the effector...
Irisin: A Hope in Understanding and Managing Obesity and Metabolic …
网页2019年8月2日 · Brown adipose tissue promotes energy expenditure by incorporating the uncoupling protein 1 (UCP1), also known as thermogenin, which decouples cellular respiration and heat production, in the mitochondrial membranes.
The cellular and functional complexity of thermogenic fat
网页Abstract. Brown and beige adipocytes are mitochondria-enriched cells capable of dissipating energy in the form of heat. These thermogenic fat cells were originally considered to function solely in heat generation through the action of the mitochondrial protein uncoupling protein 1 (UCP1).