The baculovirus replication cycle: Effects on cells and insects ...
网页These occlusion derived virions (ODV) infect midgut epithelia cells. In contrast, after transiting the midgut epithelium, the environment encountered within the insect has a near-neutral pH, and budded viruses (BV) are produced that have a different envelope structure that facilitates systemic infection.
A peptide with similarity to baculovirus ODV-E66 binds the gut
网页Baculoviruses infect their lepidopteran hosts via the midgut epithelium through binding of occlusion-derived virus (ODV) and fusion between the virus envelope and microvillar membranes. To identify genes and sequences that are involved in this process, a random phage display library was screened for …
Architecture of the baculovirus nucleocapsid revealed by cryo-EM
网页2023年11月18日 · AC144 was initially detected on both the ODV envelop (E) and capsid (C) with a molecular mass of 27 kDa, and consequently was named ODV-EC27 60. Amino acids 1-110 of AC144 demonstrate ~25%-30%...
Structural proteins of baculovirus occlusion bodies and virions
网页Below is an overview of the proteins that have been associated with major baculovirus virion structures. These include occlusion bodies, budded virus (BV) and occlusion derived virus (ODV) envelopes, and proteins that are components of nucleocapsids. Many of the latter category are shared between BV and ODV (1).
Structural Organization of Baculovirus Occlusion Bodies and …
网页2016年1月19日 · Outside the host, baculovirus occlusion bodies (OB) provide stability to occlusion-derived viruses (ODV) embedded within. The OB is an organized structure, chiefly composed of proteins namely polyhedrin, polyhedron envelope protein (PEP) and P10.
MacoNPV baculovirus midgut-specific gene expression during ... - PubMed
网页Baculoviruses have two forms, occlusion derived virus (ODV) which is responsible for primary infection in host midgut tissue and budded virus (BV), which infects all other host tissues during secondary infection. This study examined the primary infection by ODV of midgut cells of bertha armyworm Mam …
The Baculoviruses Occlusion‐Derived Virus: Virion Structure and ...
网页2007年1月10日 · Baculoviruses are transmitted to insects by the oral route mediated by the occlusion-derived virus (ODV). The ODV is also specialized to exploit the insect midgut that is one of the most extreme biological environments where the viruses are subject to caustic pH and digestive proteases.
Per os infectivity factors: a complicated and evolutionarily …
网页2017年7月27日 · In nature, occlusion-derived viruses (ODVs) initiate baculovirus primary infection in the midgut epithelium of insect hosts, and this process is largely dependent on a number of ODV envelope proteins designated as per os infectivity factors (PIFs).
Baculoviruses require an intact ODV entry-complex to resist …
网页Baculoviruses orally infect caterpillars in the form of occlusion-derived viruses (ODVs). The ODV-envelope contains a number of proteins which are essential for oral infectivity, called per os infectivity factors (PIFs). Most of these PIFs are involved in the formation of an ODV-entry complex …
Formation of ODV and polyhedra. (a) Translation of ODV envelope ...
网页The baculovirus expression vector system (BEVS) is an emerging tool for the production of recombinant proteins, vaccines and bio-pesticides. However, a system-level...
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