Designing and undertaking randomised implementation trials
网页2021年1月18日 · This article provides guidance on the key components of randomised trials of implementation strategies, including articulation of trial aims, trial recruitment and retention strategies, randomised design selection, use of implementation science theory and frameworks, measures, sample size calculations, ethical review, and trial reporting.
Evaluation and Study Designs for Implementation and Quality …
网页A fundamental goal of implementation science is to reduce the time it takes for an effective practice to go from testing in a clinical trial to use in real world health care settings.
What is the role of randomised trials in implementation science?
网页2023年8月16日 · Pragmatic trials can provide real world evidence in addressing important implementation problems and improve understanding of both complex interventions and contextual influences. There are opportunities to advance implementation science and its impact through innovative trial designs, implementation laboratories and the use of routine data.
Designing and undertaking randomised implementation trials
网页2021年1月18日 · This article provides guidance on the key components of randomised trials of implementation strategies, including articulation of trial aims, trial recruitment and retention strategies, randomised design selection, use of implementation science theory and frameworks, measures, sample size calculations, ethical review, and trial reporting.
Understanding implementability in clinical trials: a pragmatic …
网页2021年3月26日 · Implementability of trials refers to characteristics of the design, execution and reporting of a late-phase clinical trial that can influence the capacity for the evidence generated by that trial to be implemented.
Designing provider-focused implementation trials with purpose …
网页2021年1月7日 · We elaborate on nine domains that can make a provider-focused trial more explanatory or more pragmatic, including eligibility, recruitment, setting, implementation resources, flexibility of provider strategies, flexibility of intervention, data collection, primary outcome, and primary analysis.
Designing and undertaking randomised implementation trials: …
网页2021年1月18日 · This article provides guidance on the key components of randomised trials of implementation strategies, including articulation of trial aims, trial recruitment and retention strategies,...
Hybrid Effectiveness-Implementation Trial Designs: Critical …
网页Since their codification in 2012 by Curran and colleagues, hybrid effectiveness-implementation trial designs have become increasingly prevalent in implementation research. The designs’ primary purpose is to speed the translation of research evidence into routine practice, by conducting aspects of ... Since their codification in 2012 by Curran ...
Implementing a pragmatic randomised controlled trial in a …
网页6 天之前 · The study faced challenges that impacted the trial timeline and enrolment rate as presented in Fig. 2.Table 1 summarises the challenges encountered during the implementation, solutions and lessons learned. External challenges, shown in blue, included COVID-19 pandemic, repeated national strike actions, collaboration with the existing health care system and weather-related issues.
Implementation science: What is it and why should I care?
网页2020年1月1日 · Implementation trial designs differ from efficacy and effectiveness clinical trials at a fundamental level, that of the hypothesis. While clinical trials focus on contrasting the health effects of an innovation with a comparison group, implementation trials focus on testing strategies to increase uptake and sustainability of the innovation, in ...