Tribendimidine - Wikipedia
网页Tribendimidine is a broad-spectrum anthelmintic agent developed in China, at the National Institute of Parasitic Diseases in Shanghai. It is a derivative of amidantel. [1] In clinical trials, it was highly effective in treating ankylostomiasis, ascariasis and enterobiasis. [2] It is also effective against clonorchiasis. [3]
Tribendimidine: great expectations - The Lancet Infectious Diseases
网页2016年7月26日 · Tribendimidine is the first new chemotherapeutical antiparasitic drug to appear within the past 30 years and has a broad spectrum of activity against 20 different worm infections, including Taenia spp and the world's most common intestinal nematodes, such as Ascaris lumbricoides, hookworms, and Trichuris trichiura. 2 Importantly, the drug is ...
Tribendimidine: an alternative to praziquantel to treat human …
网页2017年11月16日 · Tribendimidine is an amidantel derivative acting on L-subtype nicotinic acetylcholine receptors, first discovered and developed in China more than 30 years ago. 8 Tribendimidine has broad-spectrum activity against intestinal nematodes, and the Chinese Food and Drug Administration approved this drug for …
Tribendimidine - an overview | ScienceDirect Topics
网页Tribendimidine, a symmetrical diamidine derivative of amidantel, is a broad-spectrum anthelminthic drug, developed in China in the mid-1980s [39]. The chemical structure of tribendimidine is shown in Figure 1.
The New Anthelmintic Tribendimidine is an L-type (Levamisole …
网页2009年8月11日 · In the past 30 years, only one new anthelmintic to treat human HAT infections has reached the clinic, tribendimidine. Tribendimidine, a symmetrical diamidine derivative of amidantel, is a broad-spectrum anthelmintic drug developed by the Chinese National Institute of Parasitic Diseases during the 1980s .
Efficacy and safety of tribendimidine, tribendimidine plus …
网页2017年8月29日 · The results from this randomised, controlled, single blinded, non-inferiority trial confirmed the good safety profile of tribendimidine, with only a few and mainly mild adverse events reported. The efficacy profile of tribendimidine resembles albendazole, the current standard drug against hookworm infections.
Tribendimidine: a promising, safe and broad-spectrum …
网页2005年4月1日 · We review, for the first time, a 20-year Chinese story of research and development pertaining to tribendimidine, a promising anthelmintic agent that is safe and exhibits a broad spectrum of activity. Tribendimidine was first synthesized at the National Institute of Parasitic Diseases in Shanghai in the mid 1980s.
Tribendimidine: A promising, safe and broad-spectrum
网页2005年4月1日 · Tribendimidine is considered a promising and safe anthelmintic prodrug, identified and developed in China, with broad-spectrum activity against several nematodes and the liver flukes Clonorchis...
Review Tribendimidine: a promising, safe and broad-spectrum ...
网页2005年4月1日 · We review, for the first time, a 20-year Chinese story of research and development pertaining to tribendimidine, a promising anthelmintic agent that is safe and exhibits a broad spectrum of activity. Tribendimidine was first synthesized at the National Institute of Parasitic Diseases in Shanghai in the mid 1980s.
Tribendimidine: a promising, safe and broad-spectrum …
网页2005年4月1日 · Tribendimidine was first synthesized at the National Institute of Parasitic Diseases in Shanghai in the mid 1980s. In laboratory studies, tribendimidine showed …
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