Vascular endothelial growth factor - Wikipedia
网页Vascular endothelial growth factor (VEGF, / v ɛ dʒ ˈ ɛ f /), originally known as vascular permeability factor (VPF), [1] is a signal protein produced by many cells that stimulates the formation of blood vessels.
Vascular Endothelial Growth Factor - Health Encyclopedia
网页This test measures the amount of vascular endothelial growth factor (VEGF) in your blood. VEGF is a substance that helps encourage the growth of new blood vessels. Your body makes more VEGF in certain cases.
Vascular endothelial growth factor (VEGF) - key factor in normal …
网页Both VEGF and VEGFRs are expressed not only on endothelial cells, but also on non-endothelial cells. This article aims to highlight the most recent data referring to the VEGF family and its receptors, as well as its implications in the angiogenesis process.
Vascular Endothelial Growth Factor (VEGF) and Its Role in Non ...
网页Vascular endothelial growth factor (VEGF) is a potent angiogenic factor and was first described as an essential growth factor for vascular endothelial cells. VEGF is up-regulated in many tumors and its contribution to tumor angiogenesis is well defined.
Vascular Endothelial Growth Factor - an overview - ScienceDirect
网页Vascular Endothelial Growth Factor (VEGF) is a 35–45 kDa homo-dimeric glycoprotein that plays a key role in angiogenesis, vascular permeability, and metastasis by specifically targeting endothelial cells. It exists in multiple isoforms, with VEGF-165 being the predominant form associated with tumor progression.
The function of vascular endothelial growth factor - PMC
网页Vascular endothelial growth factor (VEGF) is considered the master regulator of angiogenesis during growth and development, as well as in disease states such as cancer, diabetes, and macular degeneration.
A Structural Overview of Vascular Endothelial Growth Factors ...
网页2021年11月9日 · The vascular endothelial growth factor (VEGF) family of cytokines plays a key role in vasculogenesis, angiogenesis, and lymphangiogenesis. VEGF-A is the main member of this family, alongside placental growth factor (PlGF), VEGF-B/C/D in mammals, and VEGF-E/F in other organisms.
Biology and therapeutic targeting of vascular endothelial growth factor A
网页2023年7月25日 · Among these, vascular endothelial growth factor A (VEGFA; also known as VEGF) and its two tyrosine kinase receptors, VEGFR1 and VEGFR2, represent a key signalling pathway mediating...
The biology of VEGF and its receptors - Nature Medicine
网页2003年6月1日 · Vascular endothelial growth factor (VEGF) is a key regulator of physiological angiogenesis during embryogenesis, skeletal growth and reproductive functions. VEGF has also been implicated in...
VEGF in Signaling and Disease: Beyond Discovery and Development
网页The discovery of vascular endothelial-derived growth factor (VEGF) has revolutionized our understanding of vasculogenesis and angiogenesis during development and physiological homeostasis.