Dyserythropoiesis - Wikipedia
网页Dyserythropoiesis refers to the defective development of red blood cells, also called erythrocytes. [1] This problem can be congenital, acquired, or inherited. [2] Some red blood cells may be destroyed within the bone marrow during the maturation process, whereas others can enter the circulation with abnormalities. [3]
Dyserythropoietic anemia and thrombocytopenia - MedlinePlus
网页Dyserythropoietic anemia and thrombocytopenia is a condition that affects blood cells and primarily occurs in males. A main feature of this condition is a type of anemia called dyserythropoietic anemia, which is characterized by a shortage of red blood cells.
Dyserythropoiesis - an overview | ScienceDirect Topics
网页Dyserythropoiesis. In the bone marrow, dyserythropoiesis is defined as erythroids with multinuclearity, nuclear fragments of various sizes, abnormal nuclear shape, abnormal cytoplasmic features, such as nuclear-cytoplasmic dyssynchrony, and …
Dyserythropoiesis in the diagnosis of the myelodysplastic …
网页The majority of the dyserythropoietic features listed in the World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues were validated, although karyorrhexis was found to be infrequent and lacking in specificity; multinuclearity and megaloblastosis were more often observed but also lacked specificity.
Editorial: New insights into dyserythropoiesis: from …
网页2023年11月2日 · Erythropoiesis is a highly regulated, multistep process in which hematopoietic stem cells differentiate into mature enucleated red blood cells (RBCs), which can be divided into 3 stages: early erythropoiesis, terminal erythroid differentiation, and reticulocyte maturation ( Hattangadi et al., 2011; Dzierzak and Philipsen, 2013 ).
Clinical aspects and pathogenesis of congenital dyserythropoietic ...
网页Dyserythropoiesis is a subtype of bone marrow failure syndromes characterized by monolineage involvement and morphological abnormalities in erythroid precursor cells. The microscopic morphological evaluation justifies the heterogeneity of these syndromes (Figure 1).
Frontiers | Editorial: New insights into dyserythropoiesis: from ...
网页2023年11月1日 · Erythropoiesis is a highly regulated, multistep process in which hematopoietic stem cells differentiate into mature enucleated red blood cells (RBCs), which can be divided into 3 stages: early erythropoiesis, terminal erythroid differentiation, and reticulocyte maturation (Hattangadi et al., 2011; Dzierzak and Philipsen, 2013).
The transcription factor DDIT3 is a potential driver of ...
网页2022年12月9日 · Overexpression of DDIT3 in human healthy HSCs induces an MDS-like transcriptional state, and dyserythropoiesis, an effect associated with a failure in the activation of transcriptional programs...
Editorial: New insights into dyserythropoiesis: from …
网页2023年11月2日 · Editorial: New insights into dyserythropoiesis: from pathophysiology, molecular mechanisms to treatments for erythroid disorders. Front Cell Dev Biol. 2023 Nov 2:11:1321170. doi: 10.3389/fcell.2023.1321170. eCollection 2023. Authors. Shujing Zhang 1 2 3 , Yang Mei 4 , Baobing Zhao 1 2 3. Affiliations.
Flow cytometric detection of dyserythropoiesis: a sensitive and ...
网页2013年6月14日 · As anemia is the most frequent symptom of early MDS, the aim of this study was to identify markers of dyserythropoiesis relevant for the diagnosis of MDS analyzed by selecting erythroblasts in a...