基因序列中的一些名词区别（CDS、Exon、Intron、UTR、ORF、启 …
网页内含子 （intron）是真核生物细胞DNA中的间插序列。 这些序列被转录在前体RNA中，经过剪接被去除，最终不存在于成熟RNA分子中。 内含子和外显子的交替排列构成了割裂基因。 在前体RNA中的内含子常被称作“间插序列”。 在转录后的加工中，它比外显子有更多的突变。 内含子是一段特殊的DNA序列。 3. 外显子 （expressed region），是真核生物基因的一部分，它在剪接后仍会被保存下来，并可在蛋白质生物合成过程中被表达为蛋白质。 外显子 …
Intron - Wikipedia
网页An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product. The word intron is derived from the term intr agenic regi on, i.e., a region inside a gene. [1] . The term intron refers to both the DNA sequence within a gene and the corresponding RNA sequence in RNA transcripts. [2] .
科学网—彻底搞清楚promoter, exon, intron, and UTR - 郑俊娟的 …
网页2014年5月8日 · •An exon is asequence of DNA that is expressed (transcribed) into RNA and then often, butwith many noteworthy exceptions [1] , translated into protein. Adjacent exons maybe separated by an intron, which is later removed from the RNAtranscript via the splicing mechanism. (From Wikipedia) •UTR（UntranslatedRegions)即非翻译区，是信使RNA（mRNA）分子两端的非编码片段。
Intron - National Human Genome Research Institute
网页2 天之前 · An intron is a region that resides within a gene but does not remain in the final mature mRNA molecule following transcription of that gene and does not code for amino acids that make up the protein encoded by that gene. Most protein-coding genes in the human genome consist of exons and introns.
Introns: The Functional Benefits of Introns in Genomes - PMC
网页2015年12月31日 · Different ordinal position of introns within the gene has a different functional role. The first intron among all introns within a gene has particularly been a research focus. The first intron is the longest among all other downstream introns within a gene in most species including plants and animals [38].
Analysis of intronic and exonic reads in RNA-seq data ... - Nature
网页2015年6月22日 · RNA-seq reads that map to annotated transcripts are separated into exonic (blue) and intronic reads (red). The differences in exonic (Δexon) and intronic (Δintron) read counts between ...
The changing paradigm of intron retention: regulation, …
网页2019年12月12日 · Intron retention (IR) is a form of alternative splicing that has long been neglected in mammalian systems although it has been studied for decades in non-mammalian species such as plants, fungi, insects and viruses.
Regulation of pre-mRNA splicing: roles in physiology and ... - Nature
网页2022年12月16日 · The function of the spliceosome depends on the recognition of intronic boundaries by small nuclear ribonucleoprotein (snRNP) complexes, followed by a series of conformational transitions that...
Variations of intronic branchpoint motif: identification and …
网页2023年11月10日 · The branchpoint (BP) motif is an essential intronic element for spliceosomal pre-mRNA splicing. In mammals, its sequence composition, distance to the downstream exon, and number of BPs per 3´...
Splice and Dice: Intronic microRNAs, Splicing and Cancer
网页2021年9月19日 · Introns are segments of genetic code that are typically removed during or after transcription of RNA from DNA in a process termed splicing. As they were observed to be generally removed from mature messenger RNA (mRNA), introns were originally regarded as “junk” genetic material [10].
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