Ketolide - Wikipedia
网页Ketolides are antibiotics belonging to the macrolide group. Ketolides are derived from erythromycin by substituting the cladinose sugar with a keto-group and attaching a cyclic carbamate group in the lactone ring. [1] These modifications give ketolides much broader spectrum than other macrolides.
List of Ketolides - Generics Only - Drugs.com
网页Ketolides are a new generation of macrolide antibiotics designed to overcome issues with bacterial resistance to macrolides. They are semi-synthetic antibiotics derived from erythromycin (macrolide antibiotic) and the changes give ketolides a broader spectrum of activity. Ketolides bind to the bacterial 50S ribosomal subunit and inhibit RNA ...
Ketolides: Drug Class, Uses, Side Effects, Drug Names - RxList
网页Ketolides are a new class of antibacterial drugs (derived from macrolides) designed specifically to fight respiratory tract pathogens that are resistant to macrolides. Ketolides work by inhibiting protein synthesis and blocking the ability of bacteria to make essential proteins required for their maintenance and survival.
The ketolides: a critical review - PubMed
网页Ketolides are a new class of macrolides designed particularly to combat respiratory tract pathogens that have acquired resistance to macrolides. The ketolides are semi-synthetic derivatives of the 14-membered macrolide erythromycin A, and retain the erythromycin macrolactone ring structure as well a ….
Ketolide - an overview | ScienceDirect Topics
网页Ketolides are structurally related to macrolides, with a broader range of antibacterial activity; telithromycin is the first ketolide approved for clinical use. Macrolides and ketolides have anti-inflammatory and immunodulatory activity (including suppression of …
Ketolide - an overview | ScienceDirect Topics
网页A Ketolide is a type of antibiotic that targets the 50S subunit of the ribosome, similar to macrolides, and can overcome resistance through mechanisms like ribosomal methylation and partial active efflux.
The Ketolides | Drugs - Springer
网页2012年9月16日 · Ketolides are a new class of macrolides designed particularly to combat respiratory tract pathogens that have acquired resistance to macrolides. The ketolides are semi-synthetic derivatives of the 14-membered macrolide erythromycin A, and retain the erythromycin macrolactone ring structure as well as the D …
Macrolides and Ketolides - SpringerLink
网页2011年11月19日 · The macrolides and ketolides represent a class of antibacterial agents with activities against most Gram-positive and selected Gram-negative as well as atypical pathogens including penicillin-resistant microorganisms. Erythromycin, clarithromycin, and …
Ketolides | Antibacterial Agents*
网页Ketolides. Authors: James S. Lewis, II. , and. Karen Bush. Last updated: 13 Sep 2023. ABSTRACT. The ketolides are semisynthetic derivatives of erythromycin A, having a …
The ketolides: a critical review. | DrugBank Online
网页Ketolides are a new class of macrolides designed particularly to combat respiratory tract pathogens that have acquired resistance to macrolides. The ketolides are semi-synthetic derivatives of the 14-membered macrolide erythromycin A, and retain the erythromycin macrolactone ring structure as well as the D-desosamine sugar attached at position 5.