Mast cell - Wikipedia
网页A mast cell (also known as a mastocyte or a labrocyte [1]) is a resident cell of connective tissue that contains many granules rich in histamine and heparin. Specifically, it is a type of granulocyte derived from the myeloid stem cell that is a part of the immune and neuroimmune systems.
Mastocyte — Wikipédia
网页Le mastocyte est une cellule présente dans les tissus conjonctifs, qui fait partie du système immunitaire et se caractérise par la présence dans son cytoplasme de très nombreuses granulations contenant des médiateurs chimiques comme la sérotonine, l’histamine, la tryptase ou l’héparine.
Mastocytosis and Mast Cell Activation Disorders: Clearing the Air
网页2021年10月19日 · Mast cells orchestrate typical allergic conditions wherein activation of these cells by allergens (such as food, Hymenoptera venom, latex, antibiotics, and pollen) leads to degranulation and elaboration of inflammatory mediators, responsible for regulating the acute dramatic inflammatory response seen [6, 7, 8].
Systemic mastocytosis - Symptoms and causes - Mayo Clinic
网页2020年11月20日 · Too many mast cells can build up in the skin, liver, spleen, bone marrow or intestines. Less commonly, other organs such as the brain, heart or lungs also may be affected. Signs and symptoms of systemic mastocytosis may include: Flushing, itching or hives. Abdominal pain, diarrhea, nausea or vomiting. Anemia or bleeding disorders.
肥大细胞 - 百度百科
网页什么是肥大细胞. 肥大细胞（mast cell）为一种免疫细胞， [1]存在于血液中的这类颗粒，含有 肝素 、组胺、 5-羟色胺，由细胞崩解释放出颗粒以及颗粒中的物质，可在组织内引起 速发型过敏反应 （炎症）。 由于在肥大细胞上结合的IgE抗体和抗原的接触，使细胞多陷于崩坏。 肥大细胞呈圆形或卵圆形， 细胞核 小，呈圆形或椭圆形，染色浅，位于细胞中央。 此细胞常聚集或单个分布于血管附近。 细胞质 中充满大小一致、染成蓝紫色的颗粒， 均匀分布 …
Mast Cells, Mastocytosis, and Related Disorders
网页2015年7月9日 · Mast cells, which are major effector cells of allergic reactions, are activated through exposure to an antigen (allergen) that cross-links allergen-specific IgE, which is already bound to the...
Mast cells as a unique hematopoietic lineage and cell system: …
网页2020年8月29日 · Mast cells (MCs) are tissue-resident, multifunctional effector cells of the innate immune system that can also substantially contribute to adaptive immune responses. Historically, MCs were described and originally named by Paul Ehrlich in 1879 based on their unique dye-staining properties 1.
The mastocyte: the “other” inflammatory cell in immunopathogenesis ...
网页Mast cells are known to be the central effector cells in the elicitation of the early-phase and late-phase IgE-mediated allergic inflammatory reactions. 1,2 These cells can be activated to secrete diverse preformed mediators and de novo synthesized lipid mediators and cytokines after cross-linking of FcεRI-bound IgE with multivalent antigen.
Advances in mast cell biology: new understanding of ... - Nature
网页2009年12月30日 · Mast cells are classically viewed as effector cells of IgE-mediated allergic diseases. However, over the last decade our understanding has been enriched about their roles in host defense, innate...
The mastocyte: the "other" inflammatory cell in immunopathogenesis
网页The mastocyte: the "other" inflammatory cell in immunopathogenesis J Allergy Clin Immunol. 2004 Jul;114(1):52-7. doi: 10.1016/j.jaci.2004.04.015.
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