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网页BMJ Evidence-Based Medicine publishes original research, insights and opinions on evidence-based medicine (EBM) tools, methods and concepts. It covers topics such as shared decision making, network meta-analysis, open science and patient voices.
New evidence pyramid - BMJ Evidence-Based Medicine
网页A perspective article that challenges the traditional hierarchy of evidence in evidence-based medicine and suggests two modifications based on the GRADE framework and the JAMA User's Guide. The article argues that study design alone is insufficient to assess the quality of evidence and that systematic reviews are a lens through which evidence is viewed.
Authors - BMJ Evidence-Based Medicine
网页Learn about the editorial policies and guidelines for authors submitting to BMJ Evidence-Based Medicine, a peer-reviewed journal that publishes online. Find out about research ethics, competing interests, publication misconduct, copyright, preprints, conflicts of …
Adapt or die: how the pandemic made the shift from EBM to …
网页The paper argues that EBM+, which includes mechanistic evidence, is needed to address the complex and urgent questions of the pandemic. It critiques the limitations of RCTs and evidence hierarchies for some aspects of COVID-19 and proposes some conceptual tools and quality frameworks from other fields.
Effectiveness of tests to detect the presence of SARS-CoV-2 virus, …
网页Conclusions Evidence is rapidly emerging on the effectiveness of tests for COVID-19 diagnosis and management, but important uncertainties about their effectiveness and most appropriate application remain. Estimates of diagnostic accuracy should be interpreted bearing in mind the absence of a definitive reference standard to diagnose or rule out COVID-19 infection.
Ethical implications of AI-driven bias assessment in medicine
网页Barsby et al present a thought-provoking pilot study which discusses the application of large language models (LLMs) for automating risk-of-bias (RoB) assessments in system evaluation.1 Although LLMs show potential in streamlining evidence synthesis, the major ethical concerns caused by their integration into the medical decision-making process require careful consideration. Patient safety is ...
Postmarketing studies for COVID-19 vaccines - BMJ Evidence …
网页Vaccine development considerations for COVID-19. The normal process for developing a vaccine is broadly similar to drug development. It is lengthy and can take 10–15 years.1 Animal studies follow chemical and biological development researching the immune response; the vaccine is then tested in humans in phases I–III clinical trials.2 Assessing the efficacy of a vaccine in phase III studies ...
Responsible dissemination of health and medical research: some …
网页Dissemination has been defined as ‘the targeted distribution of information and intervention materials to a specific public health or clinical practice audience’,1 and as being ‘simply about getting the findings of your research to the people who can make use of them, to maximise the benefit of the research without delay’.2 Ethics guidelines concur that research stakeholders have ...
Understanding of research results, evidence summaries and their ...
网页To practice high quality healthcare, clinicians must be able to diagnose correctly, provide preventative and treatment interventions based on the best available evidence, and ensure decisions are consistent with patients’ values and preferences. The educational approaches to teaching evidence-based medicine (EBM) to ensure the clinical decisions reflect both the best evidence and patients ...
网页2020年7月5日 · The authors challenge the rationale for FH dietary recommendations based on the absence of support for the diet-heart hypothesis and the lack of evidence that a low saturated fat, low cholesterol diet reduces coronary events. They propose that FH individuals with insulin resistance or hypercoagulation risk should consider a low carbohydrate diet as an alternative approach.