Evaluation of 2-Thiothiazolidine-4-Carboxylic Acid, a Common
网页Methods and results: The utility and limitations of 2-thiothiazolidine-4-carboxylic acid (TTCA) as a urinary biomarker of broccoli beverage intake are tested in a randomized crossover clinical trial where 50 participants consumed either a glucoraphanin-rich (GRR) or sulforaphane-rich (SFR) beverage. Compared to run-in and wash-out periods ...
Evaluation of 2-thiothiazolidine-4-carboxylic Acid, a Common …
网页2019年6月1日 · In a clinical trial, we tested the utility and limitations of 2-thiothiazolidine-4-carboxylic acid (TTCA), an isothiocyanate-derived metabolite, as a urinary biomarker of broccoli beverage intake in a randomized crossover clinical trial where 50 participants consumed either a glucoraphanin-rich (GRR) or sulforaphane-rich (SFR) beverage.
Synthesis of 2-thiothiazolidine-4-carboxylic acid and its ...
网页1996年4月26日 · 2-Thiothiazolidine-4-carboxylic acid (TTCA), the urinary biological monitoring marker for carbon disulfide in humans was synthesized by reacting carbon disulfide with l-cystine. Validation of TTCA purity required elemental as well as mass spectral and chromatographic analyses.
The Measurement of 2-Thiothiazolidine-4-carboxylic Acid as an …
网页1996年7月15日 · The purpose of this study was to determine the potential of dithiocarbamates to release CS 2in vivo. The ability to release CS 2 was assessed by measuring urinary 2-thiothiazolidine-4-carboxylic acid (TTCA), which is used in industry to measure the exposure of workers to CS 2.
Thiazolidinediones - StatPearls - NCBI Bookshelf
网页2023年2月20日 · Thiazolidinediones are medications used to manage and treat type 2 diabetes mellitus. These medications may be acting as a nuclear transcription regulator and an insulin sensitizer. This activity illustrates the indications, mechanism of action, and contraindications for thiazolidinediones as valuable agents for managing type 2 diabetes ...
Alcohol and urinary 2-thiothiazolidine-4-carboxylic acid
网页2002年8月5日 · Introduction. Analysis of 2-thiothiazolidine-4-carboxylic acid (TTCA), an important metabolite of carbon disulfide (CS 2), is widely used in the biological monitoring of exposure to CS 2 at the workplace. TTCA was first isolated from the urine of exposed workers and confirmed by mass spectrometry (Doom et al., 1981).
Saturated Five-Membered Thiazolidines and Their Derivatives: …
网页2020年3月23日 · Thiazolidine motifs behave as a bridge between organic synthesis and medicinal chemistry and compel researchers to explore new drug candidates. Thiazolidine motifs are very intriguing heterocyclic five-membered moieties present in diverse natural and bioactive compounds having sulfur at the first position and nitrogen at the third position.
2-Thioxothiazolidine-4-carboxylic acid | C4H5NO2S2 - PubChem
网页2-Thioxothiazolidine-4-carboxylic acid | C4H5NO2S2 | CID 3034757 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Liquid chromatographic determination of 2-thioxothiazolidine-4 ...
网页1990年12月15日 · Automated column-switching high-performance liquid chromatography for the determination of 2-thiothiazolidine-4-carboxylic acid in urine. Journal of Chromatography B: Biomedical Sciences and Applications 1993 , 620 (1) , 47-53.
Identification and determination of 2-thiothiazolidine-4 …
网页Abstract. A compound was isolated from the urine of workers exposed to carbon disulfide during the production of rayon. The compound was identified as 2-thiothiazolidine-4-carboxylic acid (TTCA) by GC/MS and NMR. A HPLC method for the quantitative determination of TTCA was elaborated and applied to urine samples.
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