Device-Based Ventricular Reverse Remodeling: - JACC: Basic to ...
网页2023年1月23日 · Left ventricular (LV) mass, geometry, and architecture are prone to change in response to neurohormonal activation and physical stresses on the myocytes—a process termed ventricular remodeling. 1 Remodeling, which involves almost every aspect of cellular and extracellular biology, leads to progressive cavitary dilation and distortion of the ...
Ventricular Reshaping Strategies in Heart Failure
网页Ventricular Reshaping Strategies in Heart Failure. Update on recent and ongoing clinical trials. Approximately 64.3 million people have heart failure worldwide with an incidence and prevalence of more than 6 million, or > 2.5%. 1 In the United States, roughly 60% of cases of congestive heart failure are due to ischemic cardiomyopathy. 2 Both ...
Surgical ventricular reconstruction for ischemic …
网页2021年10月1日 · Surgical ventricular reconstruction (SVR) has been used to control adverse ventricular remodeling and improve cardiac function in ischemic cardiomyopathy. The purpose of this systematic review and meta-analysis was to collect and analyze all available evidence on the utilization and efficacy of SVR. Methods.
Transcatheter left ventriculoplasty - PubMed
网页2024年4月24日 · This review addresses the rationale for left ventriculoplasty, presents the prior surgical and percutaneous attempts in the field, provides an overview of the novel transcatheter left ventriculoplasty devices and their respective trials, and highlights potential challenges associated with establishing such device-based therapies in our ...
Reshaping the Ventricle From Within: MIRTH (Myocardial …
网页MIRTH is a novel catheter-based intramyocardial ventricular remodeling procedure. •. Intramyocardial guidewire navigation is a new technique that enables MIRTH, allowing the operator to easily steer an angioplasty guidewire to …
Transcatheter Mitral Cerclage Ventriculoplasty: From Bench to …
网页2022年6月6日 · The NHLBI Transcatheter Mitral Cerclage Ventriculoplasty Early Feasibility Study ( NCT03929913) was an Investigator-initiated prospective multicenter study in patients with mitral regurgitation and heart failure with reduced ejection fraction (HFrEF) or preserved ejection fraction (HFpEF).
Transcatheter Mitral Cerclage Ventriculoplasty: From Bench to …
网页The aim of this study was to evaluate the safety and feasibility of transcatheter mitral cerclage ventriculoplasty in patients with MR and either heart failure with reduced ejection fraction or preserved ejection fraction and in subjects with prior edge-to-edge repair but persistent or recurrent symptomatic MR.
Autophagy during left ventricular redilation after ventriculoplasty ...
网页After left ventriculoplasty, myocardial autophagy decreases early and increases again during ventricular redilation as an adaptive mechanism. Further studies are necessary to examine whether pharmacologic interventions can modulate myocardial autophagy and maintain the early unloading effect of left ventriculoplasty in ischemic cardiomyopathy.
Transcatheter Mitral Cerclage Ventriculoplasty: From Bench to
网页2022年6月27日 · Objectives: The aim of this study was to evaluate the safety and feasibility of transcatheter mitral cerclage ventriculoplasty in patients with MR and either heart failure with reduced ejection fraction or preserved ejection fraction and in subjects with prior edge-to-edge repair but persistent or recurrent symptomatic MR.
Transcatheter left ventriculoplasty | EuroIntervention
网页2023年4月24日 · Left ventriculoplasty encompasses surgical and minimally invasive procedures that directly modulate the LV geometry and promote an immediate and direct physical effect, followed by ongoing reverse remodelling as a result of reduced chamber size and wall tension.