Combining NFL picks and building NFL parlays is a common way to try to make a quick buck, but nailing NFL score predictions can be highly profitable. NFL matchups, potential game flow and NFL betting trends should all be taken into consideration before locking in Week 7 NFL game picks.

There are 15 games on the NFL slate in Week 7, beginning with the Denver Broncos and New Orleans Saints on Thursday, then continuing Sunday for the third and final London game of the season, which has the Jacksonville Jaguars hosting the New England Patriots at Wembley Stadium.

The Kansas City Chiefs (5-0) head to California to face the San Francisco 49ers (3-3) in a rematch of last season's title game. The defending Super Bowl champions are coming off a bye and rested, which could be what the team needed as it dealt with several inconsistent moments on offense while dealing with injuries.