Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role ...

Study reveals widespread dysregulation of transposable elements (TEs) in aging human brains with Alzheimer's disease, using ...

The sequencing of the human genome at the turn of the 21st century was heralded as a monumental scientific achievement ...

Research uncovers the critical role of carnitine transporters in maintaining fertility by regulating energy metabolism and ...

The most popular of these treatments aim to alter either DNA methylation or histone acetylation. Inhibitors of DNA methylation can reactivate genes that have been silenced. Two examples of these ...

A research team, delving into the impact of excessive prenatal prednisone exposure (PPE) on fetal development, discovered ...

Cholesterol lowering properties of chitosan with different degrees of acetylation (1999), Grant - University of Massachusetts Lowell Wilson, T.A. (Co-Principal) Development of atherosclerosis in ...

That is, transcriptional activation was associated with methylation at K4, which paralleled acetylation of K9 and K14, while transcriptionally inactive chromatin was associated with K9 methylation.

GlobalData’s report assesses the drugs in the Double Homeobox Protein 4 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

开发新型免疫靶点是提升免疫治疗效果的关键途径之一。徐瑞华教授研究团队在国际范围内率先提出了针对晚期胃癌的抗 CLDN18.2 治疗方案（免疫机制），为 CLDN18.2 阳性且 HER2 阴性的晚期胃癌患者开辟了新的治疗路径，显著改变了临床实践。此外 ...

CUT-Tag is used to identify super-enhancers (SEs) for the first time in gastric cancer, and the mRNA decay mechanism activated by SE-driven ZFP36L1 in infiltrative gastric cancer along with innovative ...