correlated significantly negatively with adipocyte size, subcutaneous, visceral and overall body fat measures, fasting insulin and leptin. The same was true for triglyceride synthesis and glycerol ...

Consequently, ESRRA abrogation decreased the secretion of leptin from both visceral adipocytes and BMAds, promoting BMSCs to ...

The initial discovery of leptin, an adipocyte-derived hormone that acts on hypothalamic neurons to suppress appetite and regulate energy expenditure, raised hope for an obesity therapy.

Ghrelin and leptin are two hormones naturally found in your body. Ghrelin, the "hunger hormone," tells your brain when you are hungry. Leptin, the "fullness hormone," tells your brain when you are ...

High maternal linoleic acid intake during pregnancy may impact fetal development and increase the risk of obesity and ...

Sep. 18, 2024 — A study more closely links obesity to dementia, finding that leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white ...

Regular endurance exercise significantly remodels abdominal subcutaneous fat in adults with obesity, enhancing its metabolic function and contributing to better cardiometabolic health.

The FDA also plans to hold an advisory committee for the DCCR therapy for Prader-Willi syndrome, with a PDUFA date of 27 ...

Richard J. Johnson; Takahiko Nakagawa; L. Gabriela Sanchez-Lozada; Mohamed Shafiu; Shikha Sundaram; Myphuong Le; Takuji Ishimoto; Yuri Y. Sautin; Miguel A. Lanaspa ...

Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis. Nat Commun 2021;12:4829 (* equal contribution). Zhu Y, Gao Y, Tao ...