Discovery of enzyme pathway may lead to lifesaving leishmaniasis treatments
A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more ...
Nature1 年
Fighting the rising tide of antifungal resistance: a global challenge
fumigatus, azole-resistance represents a clinically significant challenge. New classes of drugs with new mechanisms of action, like the orotomides, offer a way round the resistance that has ...
News Medical on MSN5 天
Solving a decades-long puzzle in leishmaniasis drug development
A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more ...
University of Manchester24 年
Deadly mould strains highly likely to acquire resistance to new drugs
Scientists have identified strains of one of the world’s most dangerous fungal pathogens, already resistant to our most ...
Business Insider India2 年
People are getting sick from drug-resistant mold found in their flower beds and compost ...
had evolved resistance to two or more azole drugs. Although drug resistance can emerge during treatment in hospital settings, the authors concluded that the fungi in question developed resistance ...