Researchers from the University of Innsbruck have developed a new method for covalently labeling RNA in the cell. In the ...

The Royal Swedish Academy of Sciences has decided to award this year’s Nobel Prize in Chemistry to Carolyn R. Bertozzi of Stanford University, Morten Meldal of University of Copenhagen ...

This paradigm-shifting ‘bioorthogonal chemistry’ led to the 2022 Nobel Prize in Chemistry to Bertozzi, Meldal and Sharpless. Dr Schumann’s team uses bioorthogonal chemistry to make tools that are ...

Rapid Bioorthogonal Chemistry Turn-on through Enzymatic or Long Wavelength Photocatalytic Activation of Tetrazine Ligation. Zhang H, Trout WS, Liu S, Andrade GA, Hudson DA, Scinto SL, Dicker KT, Li Y, ...

Bioorthogonal chemistry has become a mainstay technique used by chemists and biologists alike. Here we look back at one of its key reactions: strain-promoted azide–alkyne cycloadditions (SPAAC).

Protein glycosylation is a fundamental biological process that regulates various cellular functions, yet its study has been hampered by the complexity and low abundance of glycoproteins.

We are using this technology for: 1) The development of new bioorthogonal conjugation reactions, especially ones that are compatible with existing bioconjugation chemistries to enable site-specific ...

Americans Carolyn R. Bertozzi and K. Barry Sharpless, and Danish scientist Morten Meldal were cited for their work on click chemistry and bioorthogonal reactions. “It’s all about snapping ...