Zoledronic acid is a potent, new-generation bisphosphonate indicated for the treatment of documented bone metastasis in patients with solid tumors and bone lesions associated with multiple myeloma.
Chapurlat RD et al. (2007) Microcrack frequency and bone remodeling in postmenopausal osteoporotic women on long-term bisphosphonates: a bone biopsy study. J Bone Miner Res 22: 1502–1509 ...
Initial data suggests clodronate (clodronic acid) reduces the incidence of both osseous and visceral metastases in high-risk patients with breast cancer. In addition, like other bisphosphonates ...
Discontinuation of bisphosphonate therapy correlated with ... translate to other populations of patients with cancer and metastatic bone disease? According to Cesar Migliorati, Professor of ...