Many pathogenic viruses require a specific structure to be infectious, and their proteins form that structure in vivo with remarkable fidelity. The dynamical process by which protein conformations are ...

It is single-stranded and can encode instructions for viral replication. Also known as a capsid, this structure surrounds and protects the genetic material of a virus. In influenza, the coat forms a ...

The dengue virus has a roughly spherical structure. It is composed of the viral genome and capsid proteins surrounded by an envelope and a shell of proteins. After infecting a host cell ...

Select any virus below to explore its structure and biology ... These viruses have only the capsid surrounding their genetic material. A virus budding from a host cell membrane.

The basic research that led to the treatment, the text points out, provides a new understanding of the structure and function of the HIV capsid, a kind of protective shell that safeguards the ...

The award also recognizes related work surrounding gaining a new understanding of the structure and function of HIV’s capsid protein. Despite decades of advancements, HIV continues to infect ...

DNA replication techniques such as error-prone PCR or random peptide insertion can be used to generate large AAV libraries with random point mutations in their capsid structure. After screening an ...

To achieve this, the team has developed a new methodology using artificial intelligence tools, based on protein structure prediction, to predict the efficiency and stability of the new capsid.