The cell must also pass through a series of checkpoints that ensure conditions are favorable for division. In order to move from one phase of its life cycle to the next, a cell must pass through ...

CHK1 is important for the activation of S, G2 checkpoints in response to DNA damage and replicative ... We have recently generated cell lines with resistance to both in-house and external CHK1 ...

The replication fork is more than just a means for DNA duplication. It is connected to a checkpoint system that keeps the genome intact and prevents cancer. Aa Aa Aa Eukaryotic genomes are ...

A review discussing the therapeutic potentials of NK cell biology has been published in the journal Frontiers of Medicine. This exhaustion is influenced by immune checkpoint receptors, which are ...

This exhaustion is influenced by immune checkpoint receptors, which are inhibitory cell surface receptors that can suppress antitumor immunity. Notably, intracellular checkpoint molecules within ...