Translocations generate novel chromosomes, but are often linked to disorders like infertility and cancer. How do these new chromosomes generate problems, and how are they detected? Translocations ...

Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking ...

A population bottleneck approximately 900,000 years ago is thought to coincide with genomic rearrangements, the fusion of ...

(Because the translocations responsible for DS can be inherited, this form of the disease is sometimes referred to as familial DS.) In these cases, a segment of chromosome 21 is transferred to a ...

Chromosomal translocations occur in leukemias, lymphomas, sarcomas and some epithelial tumors and some generate unique fusion proteins. These translocation products may provide tumor-specific ...

The first gene in the class, subsequently named the LIM Domain Only genes (LMO), was found as a transcribed region on human chromosome 11 band p15 near to a T cell acute leukaemia chromosomal ...

Sometimes though, Wolf-Hirschhorn syndrome is caused when one of the parents has something called a “balanced translocation.” That means two or more of their chromosomes broke and switched ...

All array platforms will detect copy number variations including deletions, duplications, unbalanced translocations, some marker chromosomes and aneuploidy. SNP arrays have the added advantage of ...

The first gene in the class, subsequently named the LIM Domain Only genes (LMO), was found as a transcribed region on human chromosome 11 band p15 near to a T cell acute leukaemia chromosomal ...