Nowell and Hungerford started their search by investigating cells from individuals with acute myelogenous leukemia (AML ... 9 and 22 is called a reciprocal translocation. In Figure 1, the ...
Chromosomal translocation fusion proteins contain ... In Philadelphia chromosome-positive chronic myelogenous leukemia (CML), which fuses the BCR and ABL genes, data indicate the presence of ...
is an effective treatment for chronic myeloid leukemia (CML)—is a logical extension of earlier landmark discoveries that CML is caused by BCR-ABL, the tyrosine kinase inhibited by imatinib.
The meeting also featured discussions on patient-centered outcomes, such as quality of life and treatment costs, along with the challenges of managing advanced CML stages, including blast crisis.