Clinical trial ... of randomized controlled trials) using information on current treatments, the anticipated effect of the therapeutic intervention being studied and applying biostatistics methods.

As randomized methods continue to grow in importance, this textbook provides a rigorous yet accessible introduction to fundamental concepts that need to be widely known. The new chapters in this ...

Systematically integrate biological contextual information with causal estimates generated using Mendelian randomization Develop novel approaches to identifying, validating and prioritising potential ...

The ISCHEMIA Trial randomly assigned patients with ischemic heart disease to an invasive treatment strategy centered on revascularization with a control group assigned non-invasive medical therapy. As ...