"In this high-risk population with relapsed and refractory disease and extensive prior therapy, pirtobrutinib demonstrated ...

Particularly affected, for example, are patients with a special form of blood cancer, acute myeloid leukemia with complex karyotype (CK-AML). The chromosomes of these leukemia cells are in a state ...

Pirtobrutinib, a third-generation BTK inhibitor, showed superior progression-free survival and lower treatment ...

Pirtobrutinib improved outcomes over investigator’s choice of treatment in patients with CLL/SLL previously treated with a cBTKi.

We harnessed two single-cell multiomics methods to characterize the heterogeneity of acute myeloid leukemia with complex karyotype (CK-AML). Our data link genetic, non-genetic and functional ...