Pyro Q-CpG from Biotage gives a new dimension to DNA methylation studies by quantitatively measuring the individual degree of methylation of consecutive CpG sites consistently over time.
For human tissues, prior experimental manipulations are impractical, and genomic alterations are employed. Somatic mutations mark subclones and their fates can be reconstructed with DNA sequencing ...
A new study has punctured a longstanding assumption about the source of the most common type of DNA mutation seen in the genome--one that contributes to many genetic diseases, including cancer.
Methylation often occurs when C sits next to guanine (G) bases at so-called CpG sites in DNA. Related: 'Biological aging' speeds up in times of great stress, but it can be reversed during recovery ...
Study: DNA methylation controls stemness of astrocytes in health and ischaemia. Image Credit: Christoph Bock, Max Planck Institute for Informatics In a recent study published in the journal Nature ...