Pyro Q-CpG from Biotage gives a new dimension to DNA methylation studies by quantitatively measuring the individual degree of methylation of consecutive CpG sites consistently over time.
For human tissues, prior experimental manipulations are impractical, and genomic alterations are employed. Somatic mutations mark subclones and their fates can be reconstructed with DNA sequencing ...
A new study has punctured a longstanding assumption about the source of the most common type of DNA mutation seen in the genome--one that contributes to many genetic diseases, including cancer.
Science China Life Sciences(《中国科学:生命科学》英文版)近期在线发表了题为“Genome-wide DNA methylation landscape of four Chinese populations and epigenetic variation ...
Researchers developed CheekAge, an epigenetic clock based on buccal cells, and found it predicted mortality risk with ...
Methylation often occurs when C sits next to guanine (G) bases at so-called CpG sites in DNA. Related: 'Biological aging' speeds up in times of great stress, but it can be reversed during recovery ...
Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role ...
A Ludwig Cancer Research study has punctured a longstanding assumption about the source of the most common type of DNA ...
The sequencing of the human genome at the turn of the 21st century was heralded as a monumental scientific achievement ...
Study: DNA methylation controls stemness of astrocytes in health and ischaemia. Image Credit: Christoph Bock, Max Planck Institute for Informatics In a recent study published in the journal Nature ...