此外,蛋白在纯化过程中其构象可能发生改变,所获得的药物-靶标相互作用信息不能反映活细胞内的真实情况。而且很多蛋白很难重组表达纯化,进而限制了利用生物物理分子互作技术鉴定化合物和蛋白的相互作用。这时,也可以采用 细胞热迁移技术 (cell ...
Dimethyl sulfoxide (DMSO) is a compound used in many products, such as makeup, paint removers, cleaners, essential oils, and as a flavoring agent for certain foods. The compound is also naturally ...
Thermo Scientific* Nalgene Syringe Filters (25mm diameter) can accommodate sample volumes of 10 to 50mL. Use for culture media and additives (SFCA), buffers (CA) and alcohol or DMSO (Nylon).
Calcineurin fine tunes the balance between proliferation and differentiation of Notch-responsive progenitors in the pancreatic ducts to enable beta cell regeneration in zebrafish.
The advent of large-scale sequencing in both development and disease has identified large numbers of candidate genes that may be linked to important phenotypes. Validating the function of these ...
The facility houses the following: Liquid handling robotics (Felix) capable of si/sh/CRISPR or compound addition as well as automated cell seeding (Thermo MultiDrop), medium changes, cell fixation and ...
The Price to Earnings (P/E) ratio, a key valuation measure, is calculated by dividing the stock's most recent closing price by the sum of the diluted earnings per share from continuing operations ...