Figure 1: Interactions in the active site of AAD. It is disappointing that Westheimer's simple but elegant explanation for the decreased pK a of Lys115 is now recognized as incorrect. However ...

By Vijay Kumar Malesu Shedding light on the rare neurological disorder 'stiff-person syndrome,' review explores the complex ...

Neurotransmitters are key for synaptic transmission at axon terminals, but their transport modalities remain debated. This ...

In participants who had Parkinson’s disease or DLB, the cerebrospinal fluid had much higher levels of DOPA decarboxylase – an enzyme that helps with the production of dopamine – compared with people ...

Once full approval is granted Upstaza (eladocagene exuparvovec) will become the first disease-modifying treatment for AADC (aromatic L-amino acid decarboxylase) deficiency, as well as the first ...

Acetoacetat-Decarboxylase, das Enzym, das die Abspaltung der Carboxygruppe (CO 2) aus Acetoacetat (Acetessigsäure) unter Bildung von Aceton katalysiert (Ketonkörper). Bei gesunden Menschen werden nur ...

Purpose: The pharmacology, pharmacokinetics, clinical efficacy, and safety of rasagiline are reviewed. Summary: Rasagiline is a novel, investigational propargylamine that irreversibly and ...

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age, affecting approximately 6% of this population. [1] The clinical issues in PCOS relate to ...

A recent study has uncovered the pivotal role of the enzyme CsNADP-ME2 (NADP-dependent malic enzyme, NADP-ME) in cucumbers, ...

Bei PTC Therapeutics, Frankfurt am Main, hat Kristina Kempf eine erweiterte Führungsrolle übernommen. Seit dem 1. September ...

Tiere besitzen keine Arginin-Decarboxylase (EC 4.1.1.19), wohingegen sie in Pflanzen häufiger vorkommt als die Ornithin-Decarboxylase (EC 4.1.1.17). Durch Addition einer Aminopropylgruppe werden ...