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“铜死亡”抗癌再添实例!南京医科大学合作发文:有前景的肿瘤 ...
【导读】ES是一种高效的铜离子载体,可以将铜特异性地运输到线粒体中,破坏细胞内铜的稳态。过量的细胞内铜会导致铜诱导的细胞死亡(cuproptosis)和化学动力疗法(CDT),进而引发免疫原性细胞死亡(ICD)并激活抗肿瘤免疫响应。然而,肿瘤免疫抑制 ...
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