The sequential addition of growth factors triggered the differentiation of human pluripotent stem cells into non-neural ectoderm. This gave rise to epidermal cells, and cranial neural crest cells ...

Unlike pluripotent stem cells (capable of regenerating any cell type), these "restricted-potential" cells remain specialized according to their layer of origin (the three embryonic germ layers: ...

Pluripotent stem cells have the potential to differentiate ... bones, and heart), and ectoderm (such as nerves and skin).

Caption Ocular surface ectoderm, which is thought to be the common primordium of the lacrimal gland and cornea, is induced in zone-3 of eye-like organoids derived from human iPS cells. After ...