The peripheral endoplasmic reticulum (ER) forms a continuous ... how the unique structure of the ER arises and supports its function is critical to developing a mechanistic understanding of ...

What Does the Golgi Apparatus Do? The Golgi apparatus functions as a molecular assembly line in which membrane proteins undergo extensive post-translational modification. Many Golgi reactions ...

PDAT enzymes use membrane phospholipids as direct fatty acid donors to generate triglycerides stored in lipid droplets. This ...

The endoplasmic reticulum functions as a reservoir for calcium and carbohydrates and also serves as the site for the synthesis of various hormones. Cells adjust the expansion and networking of ...

Transient Ca2+ fluctuations on the surface of the endoplasmic reticulum (ER) can induce liquid-liquid phase separation (LLPS) ...

A protein's function directly depends on its folded ... in the sarcoplasmic reticulum — a specialized type of endoplasmic reticulum found in muscle cells. Since calcium is essential for muscle ...

The study was carried out as part of the “SCALE - Subcellular Architecture of Life" cluster initiative. The endoplasmic reticulum functions as a reservoir for calcium and carbohydrates and also serves ...

Our research group is investigating the signalling and biological functions of GDNF neurotrophic family ligands and endoplasmic reticulum located CDNF/MANF protein families, both within and outside of ...

Nearly one-third of all human proteins must be transported to the endoplasmic reticulum (ER ... which are vital for their structure and function. Disruptions in protein translocation to the ...