Here I discuss recent advances in the study of endoplasmic reticulum stress as one mechanism ... but it gradually compromises macrophage function, driving the cells to stress, inflammation and ...

The peripheral endoplasmic reticulum (ER) forms a continuous ... how the unique structure of the ER arises and supports its function is critical to developing a mechanistic understanding of ...

The endoplasmic reticulum functions as a reservoir for calcium and carbohydrates and also serves as the site for the synthesis of various hormones. Cells adjust the expansion and networking of ...

The study was carried out as part of the “SCALE - Subcellular Architecture of Life" cluster initiative. The endoplasmic reticulum functions as a reservoir for calcium and carbohydrates and also serves ...

Our research group is investigating the signalling and biological functions of GDNF neurotrophic family ligands and endoplasmic reticulum located CDNF/MANF protein families, both within and outside of ...

Nearly one-third of all human proteins must be transported to the endoplasmic reticulum (ER ... which are vital for their structure and function. Disruptions in protein translocation to the ...