But is an untoward effect on the germline likely? Wilson has considered the efficiency of transduction within the gonads, the likelihood that such a transduction event involves a germ cell (as ...

Germline development is the development of the cell lineage that gives rise to the reproductive cells, called gametes, of sexually reproducing organisms. Primordial germ cells, the founder cells ...

Researchers at Dana-Farber Cancer Institute collaborated with multiple institutions to pinpoint rare germline structural ...

The nucleus of a germline stem cell undergoes two divisions, firstly separating homologous chromosomes and secondly separating chromatids. Haploid gametes contain 23 single chromosomes.

The female gamete is called an ovum or egg. The plural is ova. Ova are produced from germline cells in the ovaries. Ovaries contain immature ova at various stages of development. Each ova is ...

The most commonly identified germline pathogenic mutations were CHEK2, ATM/BRCA2 and MITF in the clear cell RCC group, and FH and CHEK2 in the non-clear cell RCC group. Compared to the non cancer ...

An expert spoke with CURE® about the importance of information that can be gained from genetic testing for patients with breast cancer. Germline testing, or genetic testing of the DNA that a person ...

"We have been so focused on the cancer cells, the 'seeds," that we've ignored the germline—'the soil." It's now clear that focusing on the soil is critical." Although scientists have rigorously ...

In multicellular organisms, how do multiple cell types originate from one cell and one genome? A critical early cell fate decision is whether to develop as germline (reproductive) or soma ...

Activator of G-protein signaling C-terminus serves as a variable element to induce asymmetric cell division, facilitating developmental diversity among species.