Glial cells come in many forms, but three major types are currently recognized: astrocytes, oligodendrocytes and microglia. The first are primarily involved in creating the blood-brain barrier and ...

Microglia are the brain's resident immune cells. Their job is to patrol the brain's blood vessels looking for invading ...

A review of the recent evidence suggests that GLP-1 drugs, such as semaglutide, could protect brain health and cognitive ...

Diminishing energy production in aging neurons triggers senescence in nearby glial cells, which ordinarily support and protect neurons. With age, some cells in the brain enter a state of senescence: ...

The brains of mammals expend a significant amount of energy in the form of adenosine triphosphate (ATP). This is the molecule ...

By Tarun Sai Lomte New insights into brain development: study maps chromatin changes linked to psychiatric disorders in ...

The study, published today in Cell Stem Cell, is the first to report that glial cells from MS patients have intrinsic ...

The Deneen Lab seeks to unlock the enigmatic biology surrounding glial cell development and function in the brain. Beginning with developmental gliogenesis, we identified the key transcriptional ...

Researchers suggest findings could help to pinpoint cell types most vulnerable to conditions such as schizophrenia, and ...

For human tissues, prior experimental manipulations are impractical, and genomic alterations are employed. Somatic mutations mark subclones and their fates can be reconstructed with DNA sequencing ...

Michael Barresi’s research interests are focused on how glial cells help wire the nervous system in the embryonic zebrafish brain. His lab discovered that astroglial cells provide a substrate for ...