Co-release of the functionally opposing fast neurotransmitters, glutamate and GABA, from distinct synaptic vesicles within the same supramammillary synaptic terminal modulates dentate granule cell ...

Neuroprotection by sigma agonists is accomplished by a variety of mechanisms like inhibition of presynaptic glutamate release and attenuation of postsynaptic glutamate-evoked Ca2+ influx.

Adenosine A1 receptors are expressed presynaptically where they compete with A2A receptors through receptor-receptor interactions to inhibit glutamate release. Postsynaptically, A1 receptors are ...

Similarly, mimicking the effects of high-frequency stimulation by increasing intracellular Ca 2+ levels with calcimycin caused CAPS DKO neurons to spontaneously release glutamate to the same ...

A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a University of ...

A new approach to treat rosacea and other inflammatory skin conditions by inhibiting mast cells could be on the horizon.

Newron and EA Pharma sign licence for evenamide in Japan & Asia. Newron to receive up to €117 million from upfront payments, milestones and royalties.

A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a University of ...

This increases glutamate in the brain and plasma, thus reducing GABA production and release. Having a diet high in fat and cholesterol can cause changes in cell membranes that alter the release of ...