在生物学的世界里，基因编辑技术一直是科学家探索的热门领域，近年来，CRISPR-Cas系统的发现和研究为基因编辑带来了革命性的变化。CRISPR-Cas系统为原核生物提供了RNA引导的适应性免疫应答，以抵御入侵的可移动基因元件，如病毒基因组、外源质粒 ...

Messenger RNA (mRNA) serves as a blueprint for proteins. When mRNA is no longer needed, it must be degraded. Director Elena ...

Therefore, how VGLL3 functions in tumor development remains largely obscure. In this study, the researchers report that VGLL3 ...

生命科学Life scienceCell Genomics是Cell ...

Twenty-two teams were challenged to find a molecule that could bind to the RNA binding site on the NSP13 helicase, a SARS-CoV-2 replication protein that is preserved across multiple coronavirus types.

Brazilian researchers have topped a bioinformatics competition looking to find molecules that could one day function as ...

A research group led by Prof. GUO Caixia from the Beijing Institute of Genomics of the Chinese Academy of Sciences (CAS) and TANG Tie-Shan from the ...

GSK101 is a Phase 1 intended as a combination therapy with a pol theta helicase inhibitor for tumors with BRCA or other HRD mutations. IDYA does not have WW commercialization rights for this ...

This unwinding of the helix is caused by an enzyme (helicase enzyme). The enzyme RNA polymerase attaches to the DNA in a non-coding region just before the gene. RNA polymerase moves along the DNA ...