Objective To evaluate the association between thyroid disease and diabetes markers. Design Retrospective cohort study. Setting The study was conducted in a diagnostic setting where the primary care ...

Children who have two or more persistent islet autoantibodies are at high risk; 70% of them will progress to diabetes in <10 years. [4] In contrast, children with a single positive persistent ...

All five types were characterized by either fasting hyperglycemia or elevated levels of plasma ... IA-2beta, or insulin autoantibodies that identify the autoimmune process that leads to beta ...

Depending upon the outcome of Pre-POINT, the study will continue to the Phase II POINT study which will determine the efficacy of oral insulin administration in autoantibody negative high risk ...

The study, which has led to the publication of many peer-reviewed studies in high impact ... diabetes-related autoantibodies ...

This was concomitant with an increase in germinal center B cells and augmented insulin autoantibody production. The effect of PD-1 blockade on germinal centers was reduced when mice were treated with ...