Accumulating evidence indicates that epigenetic modifiers have key roles in genome-wide reprogramming and activation and repression of specific genes during mammalian germ-cell development.

"The ability to analyze ancient DNA methylation patterns beyond bones gives us a window into how tissues, especially brain cells ... changes in human evolution and the development of complex ...

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...

Two weeks after a human egg is fertilized, primordial germ cells (PGCs), which develop ... at the National Center for Child Health and Development, said the latest research marked a significant ...

It allows researchers to quickly, and cheaply, target and edit genes at precise locations along the lengthy DNA ... to “germ line” cells — those that could pass on edits to a future human.